Within the past decade several new fluoroquinolones (norfloxacin, enoxacin, ofloxacin, ciprofloxacin, pefloxacin, temafloxacin and lomefloxacin) have been introduced into therapy. All these agents share a broad spectrum of activity against a variety of pathogens which are covered with low concentrations of the compounds mentioned. Moreover, the quinolones share the advantage that they are so fa...

A total of 53 trachea, air sacs, lung, and infra orbital sinus exudates were collected from 5 commercially reared Japanese quail farms showing typical symptoms of infectious coryza. Avibacterium paragallinarum was isolated and identified using selective media and by biochemical identification methods. Biochemical identification tests such as satellitism, IMViC tests and carbohydrate fermentatio...

The postantibiotic effect (PAE) of fluoroquinolones against Staphylococcus aureus was determined in Mueller-Hinton broth and normal human serum. At both 4X and 10X the MIC, serum significantly increased the duration of the PAE in all strains tested (P less than 0.05). Reducing the pH of the serum from 7.9 to 7.2 had no effect on the PAE. Heat treating the serum (56 degrees C, 30 min) reduced th...