PURPOSE Children requiring prehospital cardiopulmonary resuscitation (CPR) after traumatic injury have been shown to have poor survival. However, outcome of children still receiving CPR on-arrival by emergency medical service to the emergency department (ED) has not been demonstrated in a published clinical series. METHODS An 11-year retrospective analysis from a level I pediatric trauma cent...

In developed countries, currently more than 80% of children with cancer survive and they are considered as cured. However, the survivors are at high risk of medical and social late effects. In Morocco, childhood cancer accounts for 3% of all cancers. The purpose of this study was to look for factors related to education in Moroccan childhood cancer survivors. This was a cross-sectional study co...

CONTEXT Women treated with chest radiation for a pediatric malignancy have a significantly increased risk of breast cancer at a young age and are recommended to have an annual screening mammogram starting at age 25 years or 8 years after radiation, whichever occurs last. OBJECTIVE To characterize the breast cancer surveillance practices among female pediatric cancer survivors who were treated...

Pediatric stroke is a very rare condition and it is a cause of significant morbidity and mortality. It is among the top ten causes of death in the pediatric population, and over half of stroke survivors experience long-term disabilities. One major challenge in the diagnosis of stroke is the fact that there are many conditions that may mimic stroke. In the pediatric population the incidence of s...

Childhood cancer survivorship is a national public health priority, with an increasing number of survivors who face late effects from both disease and treatment. As childhood cancer survivors are living into adulthood, care of the late effects associated with their diagnosis and treatment can become complex. Often these patients no longer have follow-up with the treating pediatric hospital and ...

Epilepsy surgery is common in the face of benign brain tumors, but rarely for patients with a history of malignant brain tumors. Seizures are a common sequelae in survivors of malignant pediatric brain tumors. Medical management alone may not adequately treat epilepsy, including in this group. We report four cases of patients who previously underwent gross total resection, radiation therapy, an...

OBJECTIVES To evaluate risk factors for poor functional outcome in 28-day survivors after an episode of severe sepsis. DESIGN Retrospective cohort study examining data from the Researching Severe Sepsis and Organ Dysfunction in Children: A Global Perspective trial (NCT00049764). SETTING One hundred and four pediatric centers in 18 countries. SUBJECTS Children with severe sepsis who requir...

Objective Pediatric patients with relapsed or refractory acute lymphoblastic leukemia have a poor prognosis. We here assess the response rates, adverse events, and long-term follow-up of pediatric relapsed/refractory receiving blinatumomab. Methods Retrospective analysis single-center experience blinatumomab in 38 over period 10 years. Results The median age at onset therapy was years (1-21 yea...

OBJECTIVES To review the prevalence of psychiatric syndromes in pediatric critical illness survivors as well as to summarize data on vulnerabilities and pediatric intensive care unit exposures that may increase risk of developing these syndromes. DATA SOURCES MEDLINE (1966-2009), the Cochrane Library (2009, issue 3), and PsycINFO (1967-2009) as of August 9, 2009. STUDY SELECTION Case-contro...

OBJECTIVE To evaluate self-reported health-related quality of life, anxiety, depression, and cognitive function in pediatric septic shock survivors. DESIGN A retrospective cohort study. SETTING A 14-bed tertiary pediatric intensive care unit. PATIENTS Children aged >or=8 yrs at the time of the follow-up who were admitted between 1995 and 2004 for septic shock. Inotropic and or vasoconstri...