نتایج جستجو برای: pbd

تعداد نتایج: 731  

2016
B. Sadoul A. Foucard C. Valotaire L. Labbé L. Goardon J. M. LeCalvez F. Médale E. Quillet M. Dupont-Nivet I. Geurden P. Prunet V. Colson

The composition of feed for farmed salmonids has strongly evolved during the last decades due to the substitution of fishery-derived fish oil and fishmeal by ingredients of plant origin. Little information is available regarding the effects of this transition on adaptive capacities in fish. Two rainbow trout isogenic lines, known for their divergent ability to grow on a plant-based diet (PBD), ...

امیرعلی بزمونه همایون استکانچی

این مطالعه بمنظور پاسخ به نیاز مقوله طراحی بر اساس عملکرد (PBD) به روش تحلیل لرزه اینشان میدهد. PBD و مزیت های آنرا در (ET) کارآمد و سریع، کاربرد روش تحلیل لرز های زمان دوامو ET بعنوان هدفی جنبی کارایی این روش در حوزه های غیر خطی پیچیده تر ارزیابی شد. کاربردبا مثالی از ساختمان قاب مهاربندی کمانش تاب ( پس از مدلسازی رفتار غیرخطی ،PBD مزیتهای آن دراندرکنشی تیر ها و ستونها و همچنین رفتار سخ تشونده...

2014
Khondaker M. Rahman David B. Corcoran Tam T. T. Bui Paul J. M. Jackson David E. Thurston

The pyrrolo[2,1-c][1,4] benzodiazepines (PBDs) are a family of sequence-selective, minor-groove binding DNA-interactive agents that covalently attach to guanine residues. A recent publication in this journal (Raju et al, PloS One, 2012, 7, 4, e35920) reported that two PBD molecules were observed to bind with high affinity to the telomeric quadruplex of Tetrahymena glaucoma based on Electrospray...

Journal: :Molecular cancer therapeutics 2017
Jay Harper Christopher Lloyd Nazzareno Dimasi Dorin Toader Rose Marwood Leeanne Lewis David Bannister Jelena Jovanovic Ryan Fleming Francois D'Hooge Shenlan Mao Allison M Marrero Martin Korade Patrick Strout Linda Xu Cui Chen Leslie Wetzel Shannon Breen Lilian van Vlerken-Ysla Sanjoo Jalla Marlon Rebelatto Haihong Zhong Elaine M Hurt Mary Jane Hinrichs Keven Huang Philip W Howard David A Tice Robert E Hollingsworth Ronald Herbst Adeela Kamal

Antibody-drug conjugates (ADC) are used to selectively deliver cytotoxic agents to tumors and have the potential for increased clinical benefit to cancer patients. 5T4 is an oncofetal antigen overexpressed on the cell surface in many carcinomas on both bulk tumor cells as well as cancer stem cells (CSC), has very limited normal tissue expression, and can internalize when bound by an antibody. A...

2012
Sern Wei Yeoh

Portal biliary ductopathy (PBD) is a condition in which biliary and pancreatic ducts are extrinsically compressed by collateral branches of the portal venous system, which in turn have become dilated and varicosed due to portal hypertension. While the majority of patients with PBD are asymptomatic, a minority can present with symptoms of biliary obstruction and cholangitis with the potential of...

Journal: :Cell 2003
Andrew E.H. Elia Peter Rellos Lesley F. Haire Jerry W. Chao Frank J. Ivins Katja Hoepker Duaa Mohammad Lewis C. Cantley Stephen J. Smerdon Michael B. Yaffe

Polo-like kinases (Plks) perform crucial functions in cell-cycle progression and multiple stages of mitosis. Plks are characterized by a C-terminal noncatalytic region containing two tandem Polo boxes, termed the Polo-box domain (PBD), which has recently been implicated in phosphodependent substrate targeting. We show that the PBDs of human, Xenopus, and yeast Plks all recognize similar phospho...

Journal: :Anais brasileiros de dermatologia 2012
Priscila Ishioka Sérgio Yamada Nilceo Schwery Michalany Sérgio Henrique Hirata

Pigmented Bowen's disease (PBD) is a variant of squamous cell carcinoma in situ and represents less than 2% of cases of Bowen's disease. It is characterized by a sharply demarcated, pigmented plaque with a scaly or crusted surface on intertriginous and genital areas. The authors describe a case of PBD on the penis and analyze the dermoscopic aspects of this type of lesion.

2011
Uran Chung Liz Mack Jin I. Yun Soo-Hyung Kim

Cherry blossoms, an icon of spring, are celebrated in many cultures of the temperate region. For its sensitivity to winter and early spring temperatures, the timing of cherry blossoms is an ideal indicator of the impacts of climate change on tree phenology. Here, we applied a process-based phenology model for temperate deciduous trees to predict peak bloom dates (PBD) of flowering cherry trees ...

2014
Moon-Soo Lee Purnima Anumagalla Prasanth Talluri Mani N. Pavuluri

OBJECTIVES Identifying early markers of brain function among those at high risk (HR) for pediatric bipolar disorder (PBD) could serve as a screening measure when children and adolescents present with subsyndromal clinical symptoms prior to the conversion to bipolar disorder. Studies on the offspring of patients with bipolar disorder who are genetically at HR have each been limited in establishi...

Journal: :علوم و تکنولوژی پلیمر 0
فرشید ضیایی آیدا شوشتری زاده

the thermo-oxidative degradation of two viscous liquid resins of 1,2- poly-butadiene  (1,2-pbd) and 1,4- polybutadiene  (1,4-pbd) have been studied by differential scanning calorimetry (dsc) and thermogravimetry analy-sis  (tga). to  study  further,  the  effect of flm  thickness on oxidation kinetics was periodically studied by tracing the weight of the samples to make comparison with dsc resu...

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