inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, uv radiation, stress and etc. persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from t cells. these molecules (e.g. il-6, tnf-α, il-1β and il-17) are mostly pleiotropic cytokines involved i...

ophiocoma erinaceus muller &troschel; (ophiocomidae) is part of the extensive group of echinoderm that contains bioactive metabolites. as, the anti cancer potential of brittle star saponin has not been reported against cervical cancer, the present study was conducted to evaluate the anticancer effect of extracted crude saponin. saponin extraction was conducted using conventional method such as ...

background: acute lymphoblastic leukemia (all), the most common childhood cancer with a peak incidence in children from 2-5 years old, might be associated with poor prognosis and resistance to therapy in specific cytogenetic backgrounds. foxo3a, a member of the forkhead class 'o' (foxo) transcription factors, is a main downstream target of pi3k/akt pathway which regulates different variety of b...

Peppermint has considerable commercial value and widely cultivated for essential oil production, especially menthol. The aim of this study was to determine the quantitative expression of pulegone reductase (pr), menthofuran synthase (mfs) and limonene synthase (ls) genes in menthol biosynthesis pathway in Mentha x piperita , using semiquantitative RT-PCR analysis and evaluating menthol producti...

background: the effect of probiotic bacteria ( lactobacillus acidophilus and l. casei ) as safe organisms was examined on fungal growth and aflatoxin gene regulation in aspergillus parasiticus . methods: the fungus was cultured in presence of two different concentrations of l. acidophilus and l. casei in mrs broth medium. mycelia dry weight is indicated as criteria to evaluate fungal growth. be...

background and objectives:  haplophyllum canaliculatum isan endemicand endangerediranian plant from rutaceae family. the object of this work was to study the volatile production in established shoot and callus cultures of haplophyllum canaliculatum as well as isolation, identification and sequencing of 18s rrna gene from callus culture. methods: shoot and callus cultures of h. canaliculatum wer...