IN OUR EXPERIENCE about 95 per cent of patent ducti have the typical machinery murmur, and present no problem in diagnosis. A continuous murmur maximal in the second to third left intercostal space usually means patent ductus arteriosus. Other sites usually indicate other lesions. The typical machinery murmur reflects a systolic and diastolic pressure gradient between the aorta and pulmonary ar...

IN OUR EXPERIENCE about 95 per cent of patent ducti have the typical machinery murmur, and present no problem in diagnosis. A continuous murmur maximal in the second to third left intercostal space usually means patent ductus arteriosus. Other sites usually indicate other lesions. The typical machinery murmur reflects a systolic and diastolic pressure gradient between the aorta and pulmonary ar...

The patent ductus arteriosus (PDA) is a vascular structure that connects the proximal descending aorta to the roof of the main pulmonary artery near the origin of the left branch pulmonary artery. This essential fetal structure normally closes spontaneously after birth. After the first few weeks of life, persistence of ductal patency is abnormal. The physiological impact and clinical significan...

PERATIVE treatments of uncomplicated patent ductus arteriosus are now well established, and the ductus can be safely and effectively divided in vast majority of children and young adults. In certain older patients, however, calcification of the ductus and the adjacent segments of aorta and pulmonary artery offers some technical difficulties. Under this circumstance, division of the ductus is un...

BACKGROUND There is clinical equipoise regarding post-operative management of patients with patent ductus arteriosus (PDA) without insertion of a chest drain. This study evaluated post operative outcomes of chest closure with or without a drain following Patent Ductus Arteriosus ligation among childen at Uganda Heart Instritute (UHI). METHODS This was an open label randomized controlled trial...

Ibuprofen is a well-known agent used to treat patent ductus arteriosus in preterm neonates in the first days of life. In the current case report we illustrate the potential use of ibuprofen in two preterm neonates 60 and 88 days after birth, respectively. To our knowledge, this is the first report on the effects of ibuprofen on patent ductus arteriosus in preterm newborns after months of life. ...

Patent ductus arteriosus (PDA) is a persistent patency of a vessel normally present in the fetus that connects the pulmonary arterial system to the aorta. The ductus arteriosus fails to close at birth when breathing commences and placental blood circulation is removed. Closure of the ductus arteriosus arises in response to decline pulmonary vascular resistance and increased systemic vascular re...

Three cases are presented in which aortography failed to demonstrate the presence of a moderate-sized patent ductus arteriosus in association with a large proximal left to right shunt, but without other circumstances which would tend to diminish left to right shunt flow through the ductus. The ductus was not clinically apparent in any of these cases. Failure of expression of the distal lesion i...

normal healthy children.4 The association between the fall in atrial natriuretic peptide concentration and decrease in body weight after volume reduction by haemodialysis suggests that in children volume expansion releases atrial natriuretic peptide. In preterm infants plasma atrial natriuretic peptide concentrations are considerably raised on the second day of life and decrease to normal withi...