BACKGROUND The pathogenesis of empty nose syndrome (ENS) has not been elucidated so far. Though postulated, there remains a lack of experimental evidence about the roles of nasal aerodynamics on the development of ENS. OBJECTIVE To investigate the nasal aerodynamic features of ENS andto explore the role of aerodynamic changes on the pathogenesis of ENS. METHODS Seven sinonasal models were n...

OBJECTIVE To compare the microscopic and macroscopic effects of radiofrequency, high-frequency, and electrocautery therapies with partial inferior turbinotomy in the treatment of nasal obstruction caused by inferior turbinate hypertrophy. DESIGN Nonrandomized controlled trial. SETTING Department of Otolaryngology-Head and Neck Surgery, University of Genoa. PATIENTS The study included 80 p...

A 7-year- old male child presented with the complaints of tense abdominal distension and swelling over feet since 1 month. The patient had repeated episodes of similar complaints since last two years with partial or complete relief after taking various forms of allopathic therapy. On imaging, Budd-Chiari syndrome was diagnosed which was hallmarked by occluded Inferior venacava (IVC), caudate lo...

Human turbinate mesenchymal stromal cells (hTMSCs) are novel stem cells derived from nasal inferior turbinate tissues. They are easy to isolate from the donated tissue after turbinectomy or conchotomy. In this study, we applied hTMSCs to a nonviral gene delivery system using polyethyleneimine (PEI) as a gene carrier; furthermore, the cytotoxicity and transfection efficiency of hTMSCs were evalu...

Nasal airway obstruction, a well-known cause of patient discomfort, is one of the most common presenting complaints to the otolaryngologist. The different causes of nasal airway obstruction are very wide-ranging, spanning from congenital life threatening causes to acquired benign causes. Herein, we present a case of nasal obstruction caused by widening of the posterior septum. A 52-year-old gen...