objective(s)distinction of hydatidiform moles from non-molar specimens and subclassification of hydatidiform moles as complete and partial are important for clinical practice, but diagnosis based solely on histomorphology suffers from poor interobserver reproducibility. nowadays, pathologists rely on molecular techniques, however these methods are technically difficult, relatively expensive, an...

BACKGROUND Molar pregnancy represents a significant burden of disease on the spectrum of Gestational Trophoblastic Disease (GTD). The incidence appears to be quite high in South Asia. The objective of this study was to determine the frequency of GTD, and clinical presentation, management and outcome of patients with molar pregnancy. METHODS This retrospective, descriptive study was conducted ...

Matrix metalloproteinases (MMPs) are group of enzymes thought to play an important role in trophoblastic and tumor invasion. The aim of our study was to investigate the trophoblastic expression of MMPs and p53 in normal trophoblast and hydatidiform moles (HM). Paraffin sections of 45 specimens, including 14 complete hydatidiform moles (CM), 15 partial hydatidiform moles (PM), 8 atypical partial...

Abstract The ectopic molar pregnancy is rare pathology, with anatomopathological diagnosis. Management and follow-up are similar to algorithm of intrauterus.

This is an analysis of the incidence of molar pregnancies and those of complete and partial molar pregnancies across the reproductive age range for BP Koirala Institute of Health Sciences (BPKIHS) in the period 2010-2011. Patients with molar pregnancies registered with BPKIHS from January 2008 to January 2010 were identified. The overall number of molar pregnancies registered was compared to th...

A hospital based epidemiological study of benign gestational trophoblastic disease i.e., both complete and partial hydatidiform mole was undertaken at 8 hospitals. The frequency of the disease was found to be 3.89/1000 pregnancies and was found to be higher--1 in 237 deliveries in the economically deprived women admitted to a free Government Hospital, compared to only 1 in 471 deliveries in a P...