A 70-year-old man presented with slow gait and a clumsy hand on the right side. Neurological examination revealed dystonia ideomotor apraxia in hand. mask-like face, rigidity arm, shuffling were noticed. Treatment L-dopa had no effect. He was clinically diagnosed corticobasal syndrome (CBS). Susceptibility-weighted images of brain magnetic resonance imaging showed low-intensity areas surface ce...

The purpose of this investigation was to distinguish putative effects of parietal lobe lesions on script generation, in distinction from the better known and established effects of frontal lobe lesions. Nine patients, most with excised parietal lesions, were compared to nine age, gender and education matched normal participants. Eleven patients with excised tumors of the frontal lobe were compa...

The contralateral corneal reflex may be absent in patients with a deep lesion of the parietal lobe. Frontal and temporal lobe lesions apparently do not interfere with this reflex.

BACKGROUND Damage to the right parietal lobe has long been associated with various disorders of body image. The authors have recently suggested that an unusual behavioural condition in which otherwise rational individuals desire the amputation of a healthy limb might also arise from right parietal dysfunction. METHODS Four subjects who desired the amputation of healthy legs (two right, one le...

The aim of this thesis was to develop a novel behavioural technique to disrupt parietal function in order to induce top-down cortical modulation of low-level brain structures, namely the brainstem mediated vestibuloocular reflex and the early visual cortex. The premise of the technique was based upon using stimuli that engaged overlapping neuronal networks. To this end, we employed a technique ...

http://www.sciencemag.org/cgi/content/full/308/5722/662 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/308/5722/662/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://w...

Event-related potentials (ERPs) are very small voltages recorded from the scalp which originate in the brain structures in response to specific events or stimuli. They appear as a series of peaks and troughs interspersed in the Electroencephalogram (EEG) waves. The exact neural origins and neuropsychological meaning of the P300 are imprecisely known, even though appreciable progress has been ma...

The number of people receiving facial filler injections is increasing as it relatively safe than the other cosmetic procedures. However, complications injection range from mild redness and inflammation to cerebral infarction. We report case a patient who was diagnosed with infarction intracranial hemorrhage after injection. A 61-year-old male presented emergency department ocular pain visual lo...

that these findings suggest an aberrant function in the cortical GABAergic inhibitory circuits. Sensory cortex hyperexcitability also appears to be important in the pathophysiology of myoclonus. Measuring cortical potentials in response to peripheral sensory stimulation is commonly performed to study the integrity of the central nervous system and the technique is commonly referred to as SEPs. ...