Angiotensin within the central nervous system appears to be important for the maintenance of hypertension in spontaneously hypertensive rats. This study addresses the hypothesis that blockade of AT1 receptors in the rostral ventrolateral medulla would decrease blood pressure in spontaneously hypertensive rats and that this tonically active AT1-mediated input to the rostral ventrolateral medulla...

Moss, ROBERT L., I. URBAN, AND B. A. CROSS. Microelectrophoresis OJ cholinergic and aminergic drugs on paraventricular neurons. Am. J. Physiol. 223(Z) : 3 10-3 18. 1972.-Acetylcholine, monoamines, amino acids, and antagonistic agents were applied microelectrophoretically to cells in the paraventricular (PV) nucleus of the rabbit hypothalamus. Successful drug applications and extracellular recor...

The dorsomedial hypothalamic nucleus (DMH) output pathways are revealed by using autoradiographic tracing of tritium labeled Leucine and by the recently introduced Phaseolus vulgaris leuco-agglutinin immunocytochemical method. Terminal labeling appears in the dorsal motor nucleus of the vagus, nucleus ambiguus and in the parvocellular reticular formation at the lower medullary level. Mesencepha...

Stress-induced expression of immediate early genes (IEGs) appears to be transient even if the exposure to the stressor persists. However, there are some exceptions which suggest that particular characteristics of stressors can affect the dynamics of IEG expression. We studied in selected telencephalic, diencephalic and brainstem regions the mRNA levels of two clearly distinct IEGs (c-fos and ar...