Thyroid surgery is a widely performed operation in recent two decades with complication rate less than 5% [1]. Parathyroid damage is most frequent complication of thyroid surgery because parathyroid is near to or even inside of thyroid gland, and because it is a challenge to distinguish by naked eyes. It has been reported that the incidental rate of parathyroidectomy in thyroid surgery ranges b...

BACKGROUND The potential pathogenetic significance of mitochondrial DNA (mtDNA) mutations in tumorigenesis is controversial. We hypothesized that benign tumorigenesis of a slowly replicating tissue like the human parathyroid might constitute an especially fertile ground on which a selective advantage conferred by mtDNA mutation could be manifested and might contribute to the oxyphilic phenotype...

Parathyroid specimens removed from patients with clinical hyperparathyroidism were cultured in a two-layer soft-agar system. Four patients had parathyroid hyperplasia and one had a parathyroid adenoma. Colonies grew from single-cell suspensions of each specimen. Plating efficiency ranged from 0.001 to 0.05%. No colonies grew from normal bovine parathyroid specimens. Parathormone was detected in...

1. Department of Medical Imaging, AZ KLINA, Brasschaat, Belgium Background: A 66-year-old man, known with nephrocalcinosis in his medical history, was complaining of weight loss, pain at the level of the kidneys and at the right hip. Clinical examination revealed no additional abnormalities. The initial laboratory results showed high calcium (3,5 mmol/L), and normal phosphate (1,07 mmol/L) leve...

conclusions radiofrequency ablation may be used successfully in the treatment of parathyroid adenoma when a patient cannot tolerate surgery. case presentation a 47-year-old patient was referred to our hospital (namazi hospital, shiraz, iran) in april, 2015 with intracranial hemorrhage, as well as high serum calcium and pth (parathyroid hormone) levels (12.1 mg/dl and 1062 pg/ml, respectively), ...

Hyperparathyroidism is a common disorder affecting more than hundreds of thousands of people annually. While most commonly secondary to an adenoma, it may also arise from four-gland hyperplasia or malignancy. In the case of primary hyperparathyroidism, the number of glands involved may be unknown prior to surgery. In contrast, the metabolic disorder associated with renal failure induced hyperpa...

OBJECTIVE Thyroidectomy is the most common cause of hypocalcemia. Preservation of parathyroid glands in situ is essential in preventing this complication. The aims of our study were to review patients who underwent parathyroid gland autotransplantation during thyroidectomy, and to compare hypocalcemia rates in patients with and without autotransplantation. MATERIAL AND METHODS Parathyroid gla...

The microscopical pathology of the two types of primary parathyroid hyperplasia is reviewed. The importance of the differential diagnosis between chief cell hyperplasia and adenoma is stressed. The problems of the surgical pathologist in masking this differential diagnosis of a biopsy, especially on a frozen section sample, are discussed.

Parathyromatosis, in which several nodules of hyperfunctioning parathyroid tissue form in the neck and mediastinum, is a rare cause of recurrent hyperparathyroidism. However, there are some theories regarding the origin of parathyromatosis, and seeding after rupture of the parathyroid gland capsule during surgical removal of a parathyroid lesions is the most regarded one. Herein, we report a 41...