Primary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia. Majority of cases are related to single gland adenoma. Parathyroid carcinoma, atypical parathyroid adenoma, parathyroid cysts and parathyromatosis are rare conditions that account for approximately 2% of all patients with PHPT. We report an unusual case of severe hypercalcemia due to cystic atypical parathyroid adenom...

1. Simeone DM, Sandelin K, Thompson NW. Undescended superior parathyroid gland: a potential cause of failed cervical exploration for hyperparathyroidism. Surgery 1995; 118: 949–956 2. Manley NR, Selleri L, Brendolan A et al. Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol 2004; 276: 301–312 3. Billingsley KG, Douglas LF, Doppman J...

BACKGROUND Distinction of parathyroid cancer from atypical parathyroid adenoma (APA) at operation is difficult. The aim of this study was to determine whether parathyroid cancer and APA have different operative findings and long-term outcomes. METHODS A retrospective review was undertaken of patients with suspicious or malignant parathyroid tumours treated between 1974 and 2005. Parathyroid c...

The present study describes surgical resection in 23 patients under maintenance hemodialysis with hyperparathyroidism. Twenty-three patients under maintenance hemodialysis had subtotal parathyroidectomy (s-PTx, n = 12) or parathyroid gland transplantation combined with total parathyroidectomy (Tx, n = 11) performed from January 1979 to January 1991. Their ages ranged from 8 to 63 years. The PTH...

1. The autotransplantation of parathyroid glandules into the thyroid gland and behind the musculus rectus abdominis has been successful in sixty-one per cent. of the cases in which a deficiency greater than one-half has been created. 2. In no instance has the autotransplantation succeeded without the creation of such deficiency. 3. Isotransplantation has been uniformly unsuccessful. 4. Parathyr...

We report the kindred with familial isolated hyperparathyroidism with parathyroid cancer. The proband was diagnosed as having primary hyperparathyroidism at age 43. The same disorder was also found in his daughter who had low bone mass. His son was found to have primary hyperparathyroidism by family screening. The pathological diagnosis of the resected parathyroid in both father and daughter wa...