We compare parametric and nonparametric estimation methods in the context of PBPK modeling using simulation studies. We implement a Monte Carlo Markov Chain simulation technique in the parametric method, and a functional analytical approach to estimate the probability distribution function directly in the nonparametric method. The simulation results suggest an advantage for the parametric metho...

The goal of this paper is to address the issue of non linear regression with outliers possibly in high dimension, without specifying the form of the link function and under a parametric approach. Non linearity is handled via an underlying mixture of affine regressions. Each regression is encoded in a joint multivariate Student distribution on the responses and covariates. This joint modelling a...

Nowadays, one of the most important topics in risk management of banks, financial, and credit institutions is credit risk management. In this research, the researchers used survival analytic methods for credit risk modeling in terms of the conditional distribution function of default time. As a practical task, the authors considered the reward credit portfolio of Tose'e Ta'avon Bank of Guilan P...

the paper presents a possibility formulation of oneparameter estimation that unifies some usual probability formulations. Point and confidence interval estimation are unified in a single theoretical formulation and incorporated into estimators of an omnibus form: a possibility distribution. New relationships between continuous possibility distribution and probability concepts are established. T...

Results of a simulation study of the fit of data to an estimated parametric model are reported. Three particular models including the two-parameter normal and exponential distributions, and the simple linear regression model are considered. A number of scaled versions of the least squares residuals from the regression model, and quantities that may be called residuals from the other two models ...

Depending on the representation setting, different combination rules have been proposed for fusing information from distinct sources. Moreover in each setting, different sets of axioms that combination rules should satisfy have been advocated, thus justifying the existence of alternative rules (usually motivated by situations where the behavior of other rules was found unsatisfactory). These se...

This paper proposes a semi-automatic three step information scoring process that starts from constructs representing structured pieces of information and a user query. It first identifies the constructs relevant to answer the user question, based on their similarity to the query. The relevant items are then individually scored, taking into account both the reliability of their source and the ce...

Semiparametric estimation methods are used for models which are partly parametric and partly nonparametric; typically the parametric part is an underlying regression function which is assumed to be linear in the observable explanatory variables, while the nonparametric component involves the distribution of the model's ‘error terms’. Semiparametric methods are particularly useful for limited de...