Dengue is one of the most common mosquito-borne viral illnesses in tropical areas, including Pakistan. Presentation varies from a self-limiting flu-like illness to life-threatening conditions like hemorrhagic shock and multi-organ dysfunction leading death. In absence vomiting diarrhea, electrolyte abnormalities are rare findings. Though Guillain-Barré syndrome known association presenting with...

Acute bee paralysis virus (ABPV) is a small single stranded RNA virus recently classified within the family Dicistroviridae, genus Cripavirus. Here, we describe the first study of ABPV in unhealthy bee colonies, which has been an unusual loss in adult bee population and significant honey bee mortality during the year. The aim of this study was evaluation of ABPV infection in honey bee colonies ...

Sickle cell disease is an inherited haemoglobinopathy that can affect multiple organs and systems. The most common neurological complication in sickle cell disease is stroke and silent cerebral infarcts. Peripheral nervous system involvement has been described but is exceedingly rare. Herein, we describe the case of a young woman who presented with acute flaccid paralysis and sensory loss of th...

In May 1988 the World Health Assembly adopted a resolution for the global eradication of poliomyelitis. Since then two target dates for eradication (2000 and 2003) have passed and the struggle to eradicate the poliovirus continues. Australia’s commitment to the worldwide campaign began in December 1994 with the designation of the National Poliovirus Reference Laboratory at the Victorian Infecti...

Nonpolio acute flaccid paralysis is increasing in India. To determine viral causes, we conducted cell culture and molecular analysis identification of nonpolio human enteroviruses associated with acute flaccid paralysis during March-August 2010 in northern India. The predominant nonpolio enterovirus found was echovirus 13, a serotype rarely isolated in India.

In May 1988 the World Health Assembly adopted a resolution for the global eradication of poliomyelitis. Since then two target dates for eradication (2000 and 2003) have passed and the struggle to eradicate the poliovirus continues. Australia's commitment to the worldwide campaign began in December 1994 with the designation of the National Poliovirus Reference Laboratory at the Victorian Infecti...

background & objective:  periodic paralyses are a group of rare disorders that cause temporary episodes of muscle weakness or paralysis.  hypokalemic periodic paralysis usually is transmitted by an autosomal dominant trait with more penetration in men.  hypokalemic periodic paralysis may be secondary to thyrotoxicosis, hyperparathyroidism, drug  toxicity and potassium losing states. sporadic fo...

Guillain-Barré syndrome (GBS) is a very rare immune mediated disorder which is associated with demyelination of peripheral nervous system and progressive muscle weakness that occurs mostly in previously healthy individuals. It usually presents with ascending paralysis and is severe enough to warrant hospital admission for its management. The incidence of GBS is 1.1-1.8 cases in 100,000 per year...