BACKGROUND In the fine needle aspiration cytology (FNAC) for tumors of the breast, evaluation is frequently difficult because of the thick-layered cell clusters and blood inclusion. Such problems may be resolved by the returned cell block method, but its use has not spread worldwide. Here, we examined the application of the returned cell block method to cases involving difficulty in the evaluat...

Background: Cytological examination of serous body fluids is extremely important since it throws light on the cause, presence of metastatic cells, typing of unknown cases, staging and prognosis of cancer. Aims and Objectives: 1) To study and evaluate current trends in cytological evaluation of serous effusions for various pathological conditions in a tertiary care centre. 2) To analyse their fr...

Papanicolaou was born 13 May 1883 in the city of Kymi on the island of Euboea in Greece. He was the third son of Maria Georgiou and Nikolas Papanicolaou. His father was a doctor and mayor of Kymi. In his youth, Papanicolaou studied literature, philosophy, foreign languages, and he played the violin. After high school in Athens, Greece, he studied medicine at the University of Athens in Athens. ...

PURPOSE To determine if genitourinary problems are more common in women in the first 1 to 2 months after a routine pelvic examination. METHODS This was a historical cohort study in 2 family medicine teaching clinics at an urban university. Participants included all women who received a Papanicolaou smear during calendar year 2006. Subjects included all participants for weeks 1 to 7 after thei...

OBJECTIVE The aim of this investigation was to evaluate the impact of optical spectroscopy, a new approach for the detection of cervical dysplasia, on patient well-being and satisfaction. STUDY DESIGN Patient distress and satisfaction with optical spectroscopy compared with the Papanicolaou test and colposcopically directed biopsy were measured in a volunteer sample of 314 women with no histo...

Background Morphine as a natural alkaloid (opiate) is considered as one of the problems associated with poor semen production and sperm quality. For the first time, this experimental study was carried out to evaluate the impact of intra-peritoneal injection of morphine on sperm parameters, chromatin quality and DNA integrity of spermatozoa aspirated from cauda epididymis of mice. MaterialsAndMe...

Our study aims to present the principal and the advantage of using the Liquid Based Cytology method by Cytoscreen system, as an alternative to the conventional Babes-Papanicolaou test, by reducing the false negative results frequency due to the poor quality of the smears and the epithelial cell screening by the blood elements, mucus or inflammatory exudates. A set of 1 054 female patients was a...

To assess the Papanicolaou smear as a screening test for asymptomatic gonorrhoea 311 women who had had simultaneous Papanicolaou smears and cervical cultures performed were studied. Of the 151 women who were culture-positive only 27 (18%) had a positive result by Papanicolaou smear. The presence of either endocervical or metaplastic cells did not increase the frequency with which gonococci were...

Papanicolaou smears have false-negative rates of 6 percent to 56 percent that are due, in large part, to inadequate sampling of endocervical cells. A randomized, prospective trial was conducted comparing the adequacy of Papanicolaou smears obtained with the cytobrush and Ayre spatula with smears obtained with the extended-tip spatula, as measured by the presence of endocervical cells. One hundr...