نتایج جستجو برای: panel reactive antibody

تعداد نتایج: 396266  

Journal: :The Journal of Experimental Medicine 1982
D E Wylie L A Sherman N R Klinman

The capacity of the antibody repertoire to recognize complex antigens on viral-infected cells was investigated at the level of monoclonal B cell responses. A majority of primary B cells responsive to PR8(H1N1)-infected H-2 syngeneic cells produced antibody that bound viral determinants only in the context of infected cells and not the isolated virion. An examination of the fine specificity of s...

Journal: :International journal of immunopathology and pharmacology 2008
A Vojdani

Emerging evidence has suggested environmental factors such as infections and xenobiotics and some dietary proteins and peptides in the pathogenesis of many autoimmune diseases. Considering the fact that autoantibodies can often be detected prior to the onset of a disease, in this study an enzyme immunoassay was used for measurement of antibodies against different highly purified antigens or syn...

Alireza Foromadi Gholamreza Nikbakht Hosein Ali Arab Jahangir Kaboutari, Mahdi Taheri

Abstract: The aim of the present study was to produce a polyclonal antibody against bovine serum albumin (BSA) conjugated with artemisinin. To gain an immunogenic character of artemisinin, a carboxyl group was added to it using mixed anhydride method. Then, the reactive compound of artemisinin was conjugated with BSA. The BSA+artemisinin were injected to white female New Zealand rabbits for two...

Abbas Ghaderi, Helmout Modjtahedi Mahmood Jedi Tehrani Sedigheh Sharifzadeh,

Background: Lung carcinoma is a multiple type cancer comprising of small cell and non-small cell carcinomas (NSCLC). For therapeutic and diagnostic purposes, serum monoclonal antibodies have been produced against lung cancer. Objective: To charac-terize a murine monoclonal antibody (ME3D11) reactive with human NSCLC. Methods: A murine monoclonal antibody (ME3D11) reactive with human NSCLC was s...

Journal: :Memorias do Instituto Oswaldo Cruz 2002
Herminia Y Kanamura Kathy Hancock Vanderlei Rodrigues Raymond T Damian

A study was undertaken to search for DNA recombinant Schistosoma mansoni proteins responsible for eliciting an antibody response from the host at a very early phase after infection. A S. mansoni adult worm cDNA expression library was screened using pooled sera from baboons with four weeks of infection. Based on their specific reactivity with the S. mansoni infected sera and no reactivity when t...

Journal: :Journal of Clinical Pathology 1998

2014
Steven E. Lipshultz Jayanthi J. Chandar Paolo G. Rusconi Alessia Fornoni Carolyn L. Abitbol George W. Burke III Gaston E. Zilleruelo Si M. Pham Elena E. Perez Ruchika Karnik Juanita A. Hunter Danielle D. Dauphin James D. Wilkinson

In this review, we identify important challenges facing physicians responsible for renal and cardiac transplantation in children based on a review of the contemporary medical literature. Regarding pediatric renal transplantation, we discuss the challenge of antibody-mediated rejection, focusing on both acute and chronic antibody-mediated rejection. We review new diagnostic approaches to antibod...

Journal: :Blood 1981
T Hattori T Uchiyama T Toibana K Takatsuki H Uchino

We studies the surface phenotype and the functional activities of leukemic cells from three patients with Japanese adult T-cell leukemic (ATL) using the panel of OK and anti-Tac monoclonal antibodies, which react with differentiation antigens and define functionally distinct T-cell subsets or activated and terminally differentiated T cells. The phenotype of ATL cells were determined to be OKT1+...

Journal: :Cell 2016
Iuliia Gilchuk Pavlo Gilchuk Gopal Sapparapu Rebecca Lampley Vidisha Singh Nurgun Kose David L. Blum Laura J. Hughes Panayampalli S. Satheshkumar Michael B. Townsend Ashley V. Kondas Zachary Reed Zachary Weiner Victoria A. Olson Erika Hammarlund Hans-Peter Raue Mark K. Slifka James C. Slaughter Barney S. Graham Kathryn M. Edwards Roselyn J. Eisenberg Gary H. Cohen Sebastian Joyce James E. Crowe

Monkeypox (MPXV) and cowpox (CPXV) are emerging agents that cause severe human infections on an intermittent basis, and variola virus (VARV) has potential for use as an agent of bioterror. Vaccinia immune globulin (VIG) has been used therapeutically to treat severe orthopoxvirus infections but is in short supply. We generated a large panel of orthopoxvirus-specific human monoclonal antibodies (...

Journal: :Science 2010
Wanwisa Dejnirattisai Amonrat Jumnainsong Naruthai Onsirisakul Patricia Fitton Sirijitt Vasanawathana Wannee Limpitikul Chunya Puttikhunt Carolyn Edwards Thaneeya Duangchinda Sunpetchuda Supasa Kriangkrai Chawansuntati Prida Malasit Juthathip Mongkolsapaya Gavin Screaton

Dengue virus co-circulates as four serotypes, and sequential infections with more than one serotype are common. One hypothesis for the increased severity seen in secondary infections is antibody-dependent enhancement (ADE) leading to increased replication in Fc receptor-bearing cells. In this study, we have generated a panel of human monoclonal antibodies to dengue virus. Antibodies to the stru...

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