OBJECTIVES This article attempts to cover pragmatic clinical considerations involved in the use of cannabinergic medicines in pain practice, including geographical and historical considerations, pharmacokinetics, pharmacodynamics, adverse effects, drug interactions, indications, and contraindications. Topics include molecular considerations such as the 10-fold greater abundance of cannabinoid t...

At mean 125.6 months, pain was reduced from mean of 8.7 to 0.67, p < .001. Each of three patients, two of whom were musicians, returned to full professional ability. It is concluded that volar CMC joint denervation is a useful procedure, preserving joint function and relieving pain long-term.

Thirty-seven patients with chronic back pain were entered into a randomised, 3-way, double-blind, cross-over comparison of naproxen sodium 550 mg twice daily, diflunisal 500 mg twice daily, and placebo. Each treatment was given for 14 days after a preadmission wash-out week during which only paracetamol was allowed. Patients were assessed on admission and at the end of each treatment with respe...

BACKGROUND To determine the differences of precipitating and relieving factors between migraine and tension type headache. METHODS This is a cross sectional study. We retrospectively reviewed the records of 250 migraine patients and 250 patients diagnosed as tension type headache from the specialized headache clinic in Dept. of Neurology, Dhaka Medical College Hospital. Data were collected th...

BACKGROUND To evaluate the intensity of pain, swelling and trismus after the removal of impacted lower third molars comparing two different suture techniques of the triangular flap: the complete suture of the distal incision and relieving incision and the partial suture with only one suture knot for closure of the corner of the flap and the closure of the distal incision, without suturing the r...

conclusions the addition of ketamine to intravenous fentanyl plus acetaminophen pca had not extra effects in relieving post abdominal surgery pain. results there were no significant demographic differences between two groups. pain scores (at rest, while moving and coughing) during the first 48 hours were not significantly different between two groups (p values = 0.361, 0.367 and 0.204, respecti...

A patient with complex regional pain syndrome type II was successfully treated using free anterolateral thigh flap transfer with digital nerve coaptation to the cutaneous nerve of the flap. Release of the scarred tissue and soft tissue coverage with targeted sensory nerve coaptation were useful in relieving severe pain.

1. Perform a comprehensive assessment of a pain complaint and determine the most likely pathogenesis of the pain. 2. Describe pathophysiology, clinical presentation, diagnosis, and prognosis of common chronic pain conditions, including osteoarthritis (OA), peripheral diabetic neuropathy (PDN), post-herpetic neuralgia (PHN), low back pain (LBP), and spinal cord injury (SCI) pain. 3. Establish an...

Current literature suggests that transdermal fentanyl is efficacious in relieving cancer-related pain with less opioid-related constipation than morphine for patients in the palliative care setting. However, randomised controlled trials are needed to study the drug's efficacy compared with other level-three opioids that are used to manage cancer-related pain in palliative care.

BACKGROUND Cordotomy can be effective in relieving pain for patients with mesothelioma, but the evidence to support continued provision is limited. This review forms part of the Invasive Neurodestructive Procedures in Cancer Pain pilot study: The role of cordotomy in mesothelioma-related pain in the UK. AIM/DESIGN We report on the results of the first comprehensive systematic review of the us...