A 35-year-old man of Tunisian origin complained of inflammatory arthralgia and he had noticed a progressive enlargement of his hands and feet as well as facial furrowing. On examination, he had thickening of the skin of the head and distal extremities and deep folds and furrows of the skin of the forehead (A), digital clubbing of fingers (B) and toes (C), spadelike enlargement of the hands and ...

We report the case of a 30-year-old black man with a large mass consisting of longitudinal parallel ridges and furrows on the left parietal region. A small, single, hyperpigmented macule was present at birth and gradually grew and extended over the years. Cutis verticis gyrata was suspected, and an investigation was performed to discharge the possibility of pachydermoperiostosis. However, resul...

Hypertrophic osteoarthropathy is a pathology characterized by digital clubbing of the hands and feet, extremity enlargement secondary to bone and periarticular tissue proliferation, joint pain and edema, bilateral eyelid ptosis, leonine face and skin thickness.1,2 It is classified as either primary (pachydermoperiostosis) or secondary. The primary form, or idiopathic, is considered rare, corres...

Introduction Primary hypertrophic osteoarthropathy (PHO), also known as pachydermoperiostosis, is a rare genetic disease with excessive proliferation of skin and bone at the distal parts of extremities. Features include clubbing of the digits, periostitis of the long bones, hydrarthrosis, facial skin thickening and coarse facial features. It mostly affects males and has a bimodal peak of onset:...