There is increasing interest in understanding how the phase and amplitude of distinct neural oscillations might interact to support dynamic communication within the brain. In particular, previous work has demonstrated a coupling between the phase of low frequency oscillations and the amplitude (or power) of high frequency oscillations during certain tasks, termed phase amplitude coupling (PAC)....

This paper describes the Process Algebra Compiler (PAC), a front-end generator for process-algebra-based veriication tools. Given descriptions of a process algebra's concrete and abstract syntax and semantics as structural operational rules, the PAC produces syntactic routines and functions for computing the semantics of programs in the algebra. Using this tool greatly simpliies the task of ada...

Objective: This study examines the relative risk of hospital readmission for patients receiving post-acute care (PAC) at different health care settings by utilizing an innovative big-data approach. Study design: The electronic health records of 124, 127 patients from a large-scale health care system are extracted to allow for propensity score (PS) matching. The PS method is able to put patients...

PAC-1 is an inducible, nuclear-specific, dual-specificity mitogen-activated protein (MAP) kinase phosphatase that has been shown recently to be a transcription target of the human tumor-suppressor protein p53 in signaling apoptosis and growth suppression. However, its substrate specificity and regulation of catalytic activity thus far remain elusive. Here, we report in vitro characterization of...

BACKGROUND Pancreatic adenocarcinoma (PAC) is one of the most intractable malignancies. In order to search for potential new therapeutic targets, we relied on computational methods aimed at identifying transcription factor binding sites (TFBSs) over-represented in the promoter regions of genes differentially expressed in PAC. Though many computational methods have been implemented to accomplish...

This paper presents the prior PAC-Bayes bound and explores its capabilities as a tool to provide tight predictions of SVMs’ generalization. The computation of the bound involves estimating a prior of the distribution of classifiers from the available data, and then manipulating this prior in the usual PAC-Bayes generalization bound. We explore two alternatives: to learn the prior from a separat...

Since 1970, pulmonary artery catheters (PACs) have been used in clinical practice to monitor the hemodynamic status of critically ill and injured patients. This technology was introduced and commercialized without considerable testing to determine safety and efficacy. After years of common clinical use, investigators identified potential increases in mortality associated with PAC use. For the p...

Objective. The pulmonary artery catheter (PAC) remains topic of debate. Despite abundant data, it is of note that many trials did not incorporate a treatment protocol. Methods. We retrospectively evaluated fluid balances and catecholamine doses in septic patients after the introduction of a PAC-based treatment protocol in comparison to historic controls. Results. 2 × 70 patients were included. ...

Significant adsorption of sulfamethoxazole and carbamazepine to powdered activated carbon (PAC) was confirmed by a series of adsorption tests. In contrast, adsorption of these micropollutants to the sludge was negligible. The removal of these compounds in membrane bioreactor (MBR) was dependent on their hydrophobicity and loading as well as the PAC dosage. Sulfamethoxazole exhibited better remo...

Stabilized landfill leachate contains a wide variety of highly concentrated non-biodegradable organics, which are extremely toxic to the environment. Though numerous techniques have been developed for treatment, advanced membrane filtration is one most environmentally friendly methods purify wastewater effectively. In current study, novel polymeric was produced by integrating powdered activated...