نتایج جستجو برای: p53 cua
تعداد نتایج: 42967 فیلتر نتایج به سال:
پروتئین p53 که سرکوبگر تومور نیز نامیده می شود، داری سه نقش مهم: کنترل رشد سلول، مرگ برنامه ریزی شده سلول و ترمیم dna می باشد، نقص در پروتئین p53 در اثر موتاسیون ژن p53 (تششعات، مواد شیمیایی، ویروس ها) باعث ایجاد تومور می گردد. آدنوماتوز ریوی گوسفند که تحت عنوان جاگزیکت نیز شناخته شده است، یکی از بیماری های مزمن تنفسی است که با سرطانی نمودن یاخته های تنفسی به صورت پیشرونده، تمام ریه را درگیر می...
BACKGROUND This paper explores the application of alternative approaches to economic evaluation of public health interventions, using a worked example of exercise referral schemes (ERSs). METHODS Cost-utility (CUA) and cost-consequence analyses (CCA) were used to assess the cost-effectiveness of ERSs. For the CUA, evidence was synthesized using a decision analytic model that adopts a lifetime...
Cytochrome oxidase from beef heart mitochondria is a 2O4 kDa large protein consisting of 13 subunits of which the numbers 1-111 are encoded by the mitochoridrial DNA, while the remaining subunits (IV-VIII) are encoded by the nuclear genome. The protein contains 2 iron heme groups (cytochrome a and cytochrome a3), 2 Cu centres (CUA and CUB) and 1 Zn atom. The heme groups and the CuB centre are l...
Economic evaluation in health care often involves cost-utility analysis (CUA), a method based on the cost-effectiveness criterion of dollars per Quality-Adjusted Life Year (QALY), where the quality adjustement factors for years lived in ill health are established through answers to standard-gamble questions. This paper shows that, contrary to a widely held notion, allocation of a fixed health c...
OBJECTIVES The diffusion of cost-utility analyses (CUAs) through the medical literature was examined, documenting visible patterns and determining how they correspond with expectations about the diffusion of process innovations. METHODS This study used 539 CUAs from a registry. It includes data elements comprising year of publication, the research center in which the study was performed, the ...
Agents that have shown improvements in survival in mCRPC now include abiraterone, enzalutamide, docetaxel, cabazitaxel and radium-223. Bone supportive agents and palliative radiation continue to play an important role in the overall management of mCRPC. Given the complexity, variety and importance of optimizing the use of these agents, a multidisciplinary team approach is highly recommended.
A search of MEDLINE, Cochrane, and EMBASE databases and conference proceedings (January 1988‒December 2015) were included to evaluate data and select pertinent articles on the topic. Search terms included cryptorchidism or undescended testicle as the topic of interest with an English language limit. Retrospective and prospective study designs, case series, review articles, and consensus stateme...
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