Background:  Widespread and growing sources of electromagnetic radiation raised concerns attributed to the potential adverse health risk of radiofrequency fields. Given the functional importance of the hippocampus, this study aimed to investigate the effects of electromagnetic waves radiated by mobile jammer on hippocampal expression of p21 and p53 genes as regulators of cellular apoptosis...

P53 tumor suppressor gene, also known as “genome guardian” is mutated in more than half of allkind of cancers. In this study we have investigated the controls of environmental pH for P53 genemutation in point of specific sequence which is prone to mutagenesis. The most probable cancerousmutations occur as point mutations in exons 5-8 of P53 gene. The 175th codon of P53 is the thirdmost mutated ...

Backgrounds and Aims: P53 gene is regarded important in pathogenesis of different cancers. Therefore, this study aimed to investigate the frequency of p53 gene codon 72 Arg/Pro polymorphism in women suffering from breast cancer. Materials and Methods: A total of 90 patients with breast cancer and 83 matched healthy control women participated in this case-control study. Genomic DNA was extrac...

The goal of this study was to clarify the role p16INK4a, p14ARF, and p53 protein expressions in carcinogenesis squamous cell carcinomas lip. p53, p14ARF proteins were examined 46 formaline-fixed paraffin embedded tissue specimens, which included 19 cases carcinoma lip, 14 actinic cheilitis, 13 normal mucosa. Immunoreactivity peritumoral epithelium adjacent als

: Wilms tumor (WT) is the most frequent renal of childhood and a highly responsive to chemotherapy. P53 ki67 are two important markers that have been evaluated in many cancers. The role p53 pathogenesis progression WT only partly understood. Over past decade, importance Ki-67

Background:Non-Melanoma Skin Cancer (NMSC), the most prevalent types being Squamous Cell Carcinoma (SCC) and Basal Cell Carcinoma (BCC), is the most common type of malignancy in human beings. These neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. Ultraviolet B (UVB) has a wel...

background : basal cell carcinoma is the most common form of skin cancer in men. increased marker expressions of apoptosis and cell proliferation have been found in the majority of basal cell carcinomas. our purpose was to determine whether any correlation between immunohistochemical expressions of p53 and ki-67 in different histopathological variants of basal cell carcinoma and patient’s age, ...