1,3-dialkyl 3-phenylpyrrolidine-2, 5-diones were modified to produce potential steroid sulphatase inhibitors. these modifications were aimed at producing compounds, which could be expected to bind reasonably well to the active site of the steroid sulphatase enzyme but could not be hydrolyzed readily by the enzyme due to the covalent s-c bond present. in this regard the sulphinic acid derivative...

htlv-1 is the causative agent for a neurologic disease named htlv-i- associated myelopathy/tropical spastic paraparesis (ham/tsp). paraparesis of the lower limbs which appears gradually is the most common clinical feature of this disease. it has been shown that the indirect involvement of the nervous system by lymphocytes is more probable than the direct attack of the virus to the neurons. htlv...

the genus tanacetum is one of the most important medicinal plant that contains 26 species in iran, 12 of them are endemic. this paper reports the essential oil (eo) composition of tanacetum polycephalum subsp. polycephalum growing wild in iran.  flowers and leaves were collected from different location of azerbaijan province (marand, mianeh and tabriz), hydro-distilled to produce the oils and a...

trehalose is an important disaccharide signal metabolite in plants which is involved in various aspects of plant function such as response to stress, photosynthesis and carbon allocation and partitioning. a mutant of arabidopsis lacking trehalose-6-phosphate synthase activity (tps1) accumulates ascorbate. exogenous ascorbate application ameliorates trehalose induced growth inhibition of wild ty...

human resource productivity is an important subject in theory and practice, so increase of productivity is the first priority in most of organizations. the main purpose of most organizations is creating value for their shareholders. so it is necessary to understand effect of human resource productivity in achieving this goal and find the obstacles. the purpose of this research is examining the ...

objective: epilepsy is a chronic neurological disorder requiring long term therapy using antiepileptic medications. reports have incriminated long term antiepileptic drugs use in deficiency of vitamin d and bone diseases in all age groups. to investigate the association between serum 25-hydroxyvitamin d levels and pediatric epilepsy in indian patients.           methods& methods: we prospective...

in order to compare sampling efficiencies of total and inhalable dust methods, three airborne dust sampling systems , 7-hole sampler , close and open face filter cassette were compared side-by-side , as stationary and for the personal samplers , in a wood working industry to evaluate their relative efficiency. a total of 162 samples were collected. the study of particle size distribution by cas...

i n s u p p o r t i n g e n v i r o n m e n t a l s u s t a i n a b i l i t y, m a n a g i n g p r o d u c t r e t u r n s h a s b e c o m e a v e r y i m p o r t a n t a n d c h a l l e n g i n g i s s u e. r e s p o n d i n g t o t h i s t r e n d, r e s e a r c h e r s i n m a n y p a r t s o f t h e w o r l d h a v e c o n d u c t e d n u m e r o u s s t u d i e s i n r e v e r s e l o g i ...

the postharvest vase life of cut roses was studied to determine the effects of various physiological factors that influence the vase life of cut flower. cut roses were obtained from commercial area of siliguri. to assess the effect of preservatives on the postharvest life of rose, cut flowers were treated with following preservative solutions: fixed amount of citric acid (ca) (300 mg/ml) and 8-...

background cervical cancer is one of the leading causes of cancer-related death in females. human papilloma virus (hpv) is the major risk factor of cervical cancer. objectives the aim of the current study was to explore the frequency and role of 23 different hpvs in patients with cervical cancer. materials and methods overall, 117 formalin-fix and paraffin-embedded (ffpe) tissues from cervical ...