Many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative diseases. Oxidative stress can induce neuronal damages, modulate intracellular signaling and ultimately leads to neuronal death by apoptosis or necrosis. To review antioxidants preventive effects on oxidative stress and neurodegenerative diseases we accumulated data from internatio...

Hypothesis: Nowadays, rectal cancer is an important healthcare challenge that affects many thousands of people each year worldwide, being diagnosed especially after the age of 50 years. Objective: This study attempted to evaluate the oxidative stress in patients with rectal cancer. Methods and results: 30 patients from the "Prof. Dr. Al. Trestioreanu" Institute of Oncology in Bucharest were tre...

Mitochondria play an important role in controlling the bioenergetic status of cells in physiological conditions. Consequently, mitochondrial dysfunction leads to a range of human vascular diseases in humans. Although the molecular mechanisms responsible for mitochondria-mediated disease processes are not altogether clear, oxidative stress appears to be closely linked to the subsequent increase ...

o bjectives: temporomandibular dysfunction (tmd) is a group of disorders in the facial region and temporomandibular joint (tmj). biomarkers are assumed to play a role in pain and early detection of destruction. the aim of this study was to compare the saliva and serum antioxidant levels in patients with tmd and healthy subjects. mat erials and methods : this case-control study was conducted on ...

cyfluthrinm[cyano[4-fluoro-3-phenoxyphenyl]-methyl-3-[2,2-dichloroethenyl]-2,2-dimethyl-cyclo propane carboxylate] is a synthetic pyrethroid insecticide, that has both contact and stomach poison action. the present study evaluated the long-term toxic effects of cyfluthrin on antioxidant status in buffalo calves. oral administration of cyfluthrin at a dose rate of 10 and 20 mg/kg/d for 11 consec...

Since the great bulk of evidences regarding oxidative stress associated with chronic renal failure (CRF) came from haemodialysis patients and only scant data is available concerning peritoneal dialysis, we investigated the oxidative status in CRF patients on continuous ambulatory peritoneal dialysis (CAPD). Plasma lipid peroxidation assayed as thiobarbituric acid reactive substances (TBARS; nmo...

Dietary antioxidants may be useful in counteracting the chronic inflammatory status in neurodegenerative diseases by reducing oxidative stress due to accumulation of reactive oxygen species (ROS). In this study, we newly described the efficacy of a number of dietary antioxidants (polyphenols, carotenoids, thiolic compounds, and oligoelements) on viability of neuronal PC12 cells following Nerve ...