It is expected that use of adult multipotential mesenchymal stem cells (MSCs) for bone tissue engineering (TE) will lead to improvement of TE products. Prior to clinical application, biocompatibility of bone TE products need to be tested in vitro and in vivo. In orthopedic research, sheep are a well-accepted model due to similarities with humans and are assumed to be predictive of human outcome...

A series of N-heterocyclic dipeptide aldehydes 4-13 have been synthesised and evaluated as inhibitors of ovine calpain 1 (o-CAPN1) and ovine calpain 2 (o-CAPN2). 5-Formyl-pyrrole 9 (IC(50) values of 290 and 25nM against o-CAPN1 and o-CAPN2, respectively) was the most potent and selective o-CAPN2 inhibitor, displaying >11-fold selectivity. The amino acid sequences of o-CAPN1 and o-CAPN2 have bee...

From meat retails in Mosul province, forty-five meat samples of local ovine and bovine (23 bovine samples and 22 ovine samples) were collected. The period of collection was during November 2010 to May 2011, by means of multistage random sampling for detection of streptomycin residues. Enzyme linked immunosorbent assay (ELISA) was used for detection of streptomycin residues. The results revealed...

Partetravirus is a recently described group of animal parvoviruses which include the human partetravirus, bovine partetravirus and porcine partetravirus (previously known as human parvovirus 4, bovine hokovirus and porcine hokovirus respectively). In this report, we describe the discovery and genomic characterization of partetraviruses in bovine and ovine samples from China. These partetravirus...

The aim of this study was to shed light in to the complexity of the ovine colostrum proteome, with a specific focus on the low abundance proteins. The ovine colostrum is characterized by a few dominating proteins, as the immunoglobulins, but it also contains less represented protein species, equally important for the correct development of neonates. Ovine colostrum, collected immediately after ...

sheep (ovine) pulmonary adenocarcinoma (spa), also known as ovine pulmonary adneomatosis (opa),jaagsiekte and ovine pulmonary carcinoma (opc) is a contagious lung tumor in sheep and, more rarely, ingoats. this study was carried out in khuzestan, in the southwest of iran for a period of six months. a totalnumber of 3985 native breed goats were clinically inspected and postmortem examination was ...

background: pre-clinical investigation of stem cells for repairing damaged myocardium predominantly used rodents, however large animals have cardiac circulation closely resembling the human heart. the aim of this study was to evaluate whether spect/ct myocardial perfusion imaging (mpi) could be used for assessing sheep myocardium following an acute myocardial infarction (mi) and response to int...

background: the aim of this study was to investigate the role of oxidative stress in the pathology of ovine dicrocoeliasis. methods : during dec 2013 - oct 2014, seventy-two sheep (1-3 years) with liver dicrocoeliasis along with 47 healthy sheep were selected from animals admitted for slaughtering at slaughterhouse located in neyshabour, razavi khorasan province, iran. results : in comparison t...

The primary structure of ovine hypothalamic hypophysiotropic luteinizing hormone-releasing factor, LRF, has been established as pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH(2) by hydrolysis of the peptide with chymotrypsin or pyrrolidone-carboxylylpeptidase and by analysis of the products by an Edman-dansylation sequencing technique, as well as by mass spectrometry of the derived phenylthiohydan...

Two experiments were conducted to study the efficiency of ovine follicular fluid (OFF) and age ewe on in vitro nuclear maturation Awassi sheep oocytes (Experiment 1) subsequent stages early embryos their quality 2). The OFF has been added basic medium (TCM-199) with three different levels (A: 0% (Control group), B:15%, C:25% D:50%) while ages ewes determined into two main groups (> 2 1-2 yea...