The presence and location of carcinoembryonic antigen (CEA) was examined in tissue sections of 14 mucinous and 13 serous cystadenomas and cystadenocarcinomas of the ovary. CEA was demonstrated in the mucinous tumors but was not present in the serous tumors. In the mucinous tumors, CEA was located in the glycocalyx and apical portions of the absorptive-type epithelium, with only trace quantities...

Muir-Torre syndrome (MTS) is a rare inherited cancer syndrome with variable penetrance. MTS follows an autosomal-dominant pattern of inheritance, and is a subtype of Lynch syndrome [formally known as hereditary non-polyposis colorectal cancer (HNPCC)]. MTS is caused by mutations in one of several mismatch repair genes. Patients typically present with sebaceous neoplasms (sebaceous adenoma, seba...

as a tumor composed of admixed benign epithelial and malignant nonepithelial components, and this tumor usually develops as a solitary lesion in the uterine corpus (1). These neoplasms can develop in the endometrial tissue as well as in the ectopic foci of endometriosis. Rare extrauterine müllerian adenosarcomas have been reported to arise in the ovary, cervix, vagina, pelvis, bladder and colon...

Ovarian steroid cell tumours (not otherwise specified) are rare neoplasms of the ovary and are classified under lipid cell tumours. Their diagnosis can be considered as one of exclusion. Histopathologically, the tumour should carefully be evaluated for microscopic features of malignancy, but it is essential for the clinician and the pathologist to remember that in these tumours, pathologically ...

spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. spindle cell neoplasms can affect the oral cavity. in the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. this article aims to review the spindle cell neoplasms of the oral cavity with emphasis on histopathology.  ...

Background: Malignant Brenner tumour (MBT) is a rare ovarian epithelial malignancy that accounts for <0.05% of all neoplasms. Most cases are limited to the ovary and fallopian tube lymph node metastasis uncommon. Aims: We present case 65-year-old woman who was diagnosed with metastatic MBT in supraclavicular node. Methods: She initially 6 years earlier managed total abdominal hysterectomy bilat...

An immunoperoxidase technique has been utilised for the demonstration of follicle stimulating hormone (FSH), luteinising hormone (LH) and prolactin (PRL) binding sites in normal human ovaries and in a wide range of benign and malignant epithelial tumours of the ovary. The incidence of FSH, LH and PRL binding was, respectively, 32%, 41% and 39% in normal ovaries, 30%, 18.5% and 22.5% in benign e...

Ovaries are paired structures with an embryological, anatomic and functional complexity. Changes in their volume can be observed at ovulation, pregnancy and after menopause. Ovaries are normally resistant to diseases, but still ovary can be seat of more number of neoplastic lesions of benign and malignant. They may be primary or secondary, large or small, solid or cystic and also of mixed patte...

often involved in tumorigenesis. Recent exhaustive cDNA microarray analyses in human neoplasms expanded knowledge of such molecules. Hepatocyte nuclear factor-1ß (HNF-1ß) is a homeobox transcription factor that functions as a homodimer or heterodimer with HNF-1α. In contrast to HNF-1α, HNF-1ß is very weakly expressed in the liver and is commonly expressed in the kidneys. During human embryonic ...

OBJECTIVES The objectives were to determine the time course for ovarian failure in rats caused by 4-vinylcyclohexene diepoxide (VCD) and develop a model for ovarian cancer in which ovarian neoplasms were chemically induced in an animal that was follicle depleted, but retained residual ovarian tissue. METHODS Initially, female Fisher 344 rats were treated with VCD (to induce ovarian failure) o...