OBJECTIVE To assess associations of Chlamydia trachomatis and Mycoplasma genitalium antibodies with epithelial ovarian tumors. METHODS Plasma samples from 291 women, undergoing surgery due to suspected ovarian pathology, were analyzed with respect to C. trachomatis IgG and IgA, chlamydial Heat Shock Protein 60-1 (cHSP60-1) IgG and M. genitalium IgG antibodies. Women with borderline tumors (n=...

Ubiquitin-conjugating enzymes E2 (UBE2) have been reported in the microenvironment of various malignant tumors, but their correlation with ovarian cancer (OC) remains elusive. This study aimed to s...

PURPOSE The purpose of this research was to examine the DNA methylation profiles of primary sporadic ovarian cancers and ovarian tissues from high-risk women. EXPERIMENTAL DESIGN We analyzed the DNA methylation status of nine cancer-related genes in 49 primary ovarian tumors, 39 nonmalignant ovarian tissues obtained from 16 women with no known risk and from 23 high-risk women with a strong fa...

Aim: Ovarian fibroma, fibrothecoma and thecoma are benign neoplasia of the ovary. The aim this study is to analyze clinical characteristics, histopathological results surgical management ovarian fibroma/fibrothecoma.Materials Methods: This a retrospective 51 cases who underwent treatment because adnexial mass. reported as fibroma/fibrothecomas were analyzed.Results: mean age patients 58.7 years...

Ovarian epithelial cancer is a leading cause of death among gynaecological malignancies due mainly to advanced stage at presentation. Aim of the work: The purpose of this study was to investigate the expression and prognostic significance of CD44v6, Bcl-2 and P53 in ovarian tumors of low malignant potential (LMP) and primary epithelial ovarian carcinomas Experimental Design: We analyzed the imm...

Purpose: The purpose of this research was to examine the DNA methylation profiles of primary sporadic ovarian cancers and ovarian tissues from high-risk women. Experimental Design: We analyzed the DNA methylation status of nine cancer-related genes in 49 primary ovarian tumors, 39 nonmalignant ovarian tissues obtained from 16 women with no known risk and from 23 high-risk women with a strong fa...

Pseudomyxoma peritonei is only rarely seen in conjunction with primary ovarian tumors. It has been suggested that only ruptured mucinous tumors arising in ovarian mature cystic teratomas can result in this clinical picture. We describe a case of a late invasive recurrence of a mucinous intestinal-type borderline ovarian tumor arising from a mature teratoma after complete surgical debulking. Bor...

BACKGROUND Human papillomavirus (HPV) is the causal factor for cervical cancer. However, the role of HPV infection in ovarian cancer is unclear. OBJECTIVES This study aimed to determine the presence of human papillomavirus-16 (HPV-16) in ovarian tumor tissues. PATIENTS AND METHODS This was a retrospective study, which included 61 Archived human ovarian tumor tissues embedded in paraffin blo...

OBJECTIVE To detect the expression and clinical significances of Lewis y antigen and integrin αv, β3 in epithelial ovarian tumors, and to explore the expression correlation between Lewis y antigen and integrin αv, β3. METHODS Immunohistochemical staining was performed in 95 cases of epithelial ovarian cancer, 37 cases of borderline tumors, 20 cases of benign tumors, and 20 cases of normal ova...