The aim of our studies was to examine whether IGF-binding protein (IGFBP)-4 is involved in the control of the secretion of various ovarian substances and also the mediation of the effects of several hormones and growth factors on this secretion. For this purpose, we carried out the transfection of porcine granulosa cells with a cDNA sense construct, increasing IGFBP-4 synthesis. We then compare...

The low-molecular-weight stimulator of phosphofructokinase [Van Schaftingen, Hue & Hers (1980) Biochem. J. 192, 887-895] has been purified from rat liver. It was completely destroyed upon incubation with 0.01 M-HCl for 10min at 200C and fructose 6-phosphate and a reducing power equivalent in amount to the acid-labile organic phosphate were formed. It was therefore tentatively identified as fruc...

background: this study was undertaken to evaluate the role of day 3 fsh/lh ratio and day 3 lh level as predictors of ivf cycle outcomes. methods: this prospective observational study was undertaken in the ivf and reproductive biology centre and lok nayak hospital, affiliated to maulana azad medical college, in new delhi, india. the study included 105 women who underwent controlled ovarian hyper...