Computational models are commonplace in engineering gelds. The predictive ability of such models can bs improved by tuning them to experimental data. To that extent, the user must consider if the dynamics model possess the capacity to represent the dominant physics in the system. A pseudo dynamic stiffness finite element model will be used to rep-t the dynamics of the harmonically forced system...

Lonidamine is a dechlorinated derivative of indazole-3-carboxylic acid which preclinically synergizes with hyperthermia. Clinically, this nonmyelosuppressive drug (given p.o. daily) is active as a single agent in a variety of malignancies. On this basis, a Phase I study which incorporates a drug escalation schema as well as an escalation in temperature, i.e., 41.0°Cfor 85 min to 41.8°Cfor 75 ...

1. Halupczok J, Kluba‐Szyszka A, Bidzinska‐Speichert B, Knychalski B. Ovarian hyperstimulation caused by gonadotroph pituitary adenoma – Review. Adv Clin Exp Med 2015;24:695‐703. 2. Roberts JE, Spandorfer S, Fasouliotis SJ, Lin K, Rosenwaks Z. Spontaneous ovar ian hypers t imula t ion caused by a follicle‐stimulating hormone‐secreting pituitary adenoma. Fertil Steril 2005;83:208‐10. 3. Pentz‐Vi...

The GH gene and BMP15 gene have been used as candidate genes for ­marker-assisted selection in different livestock species. Random blood samples were obtained from 180 Zel sheep breed to study genetic polymorphism of these genes. DNA was extracted from blood samples and a 365 bp fragment from the exon V of the ovine growth hormone gene and a 312 bp region from exon II of BMP15 gene were amplifi...

Recent studies have demonstrated that advanced neoplastic disease is often associated with a general impairment of im mune function (15, 17, 29). High levels of serum immunoreg ulatory factors which nonspecifically inhibit in vitro and in viva lymphocyte function (13, 17, 21 , 25, 28, 39, 40, 45) are thought to account for the depressed immune status of anergic cancer patients (13, 33). Further...

In the chicken, serum gamma globulin (CGG) is preferentially transferred by the follicular epithelium of the ovary to the developing ova. The concentration of gamma globulin in the yolk of the unfertilized egg is many times the concentration of chicken serum albumin (CSA). This transfer occurs largely during the 4 to 5 days preceding ovulation when the growth of the ovum is most rapid. Thus, in...

In the chicken, serum gamma globulin (CGG) is preferentially transferred by the follicular epithelium of the ovary to the developing ova. The concentration of gamma globulin in the yolk of the unfertilized egg is many times the concentration of chicken serum albumin (CSA). This transfer occurs largely during the 4 to 5 days preceding ovulation when the growth of the ovum is most rapid. Thus, in...