PURPOSE To reduce the adverse effects and high frequency of administration of propranolol to treat infantile hemangioma, we first utilized propranolol-loaded liposomes-in-microsphere (PLIM) as a novel topical release system to realize sustained release of propranolol. METHODS PLIM was developed from encapsulating propranolol-loaded liposomes (PLs) in microspheres made of poly(lactic-co-glycol...

Cardiac hemangioma is a rare primary benign tumour, localised in the right atrium in 23% of cases. In a 60-year-old patient, who complained of remote chest discomfort and recent exertional palpitation, a right atrial mass was discovered by magnetic resonance imaging and echocardiography. A selective operation was performed and the tumour was resected. Histology revealed it to be a cavernous hem...

We describe a very unusual vertebral hemangioma presenting with a mixture of aggressive-like pattern (epidural extension, T1 hyposignal) and quiescent, inactive lesion (fatty infiltration), in association with a spiculated calcified epidural component.This paper emphasizes that CT and/or MR findings are accurate enough to make formal assessment of vertebral hemangioma, preventing patient's angu...

Pyogenic granuloma (lobular capillary hemangioma) is a common acquired vascular lesion of the skin and mucous membranes in the pediatric age group. Pyogenic granuloma and hemangioma of oral cavity are wellknown benign lesions. The clinical diagnosis and differentiation of these lesions is at times difficult. The purpose of this article is to report an unusual case of benign tumor occuring on ha...

OBJECTIVES/HYPOTHESIS Objectives were 1) to review the presentation, natural history, and management of subglottic hemangioma; 2) to assess the affect of five variables (age, gender, degree of subglottic narrowing, location and extent of subglottic hemangioma, and lack or presence of other hemangioma) and the outcome of six different treatment modalities (conservative monitoring, corticosteroid...

INTRODUCTION Hepatic and splenic hemangiomas are common benign tumors that mainly affect female patients. Giant splenic hemangiomas are extremely rare, especially when correlated with multiple hepatic hemangiomas. Pathogenetic mechanisms between hemangiomas and oral contraceptives, as well as therapeutic approaches, are analyzed in this case report, in particular for the management of synchrono...

Hemangioma is a common soft tissue lesion in the head and neck region. Hemangioma in the context of minor salivary glands is rarely encountered in surgical pathology practice, and for this reason most pathologist are often unfamiliar with its histomorphological features. We report a rare histological finding of salivary gland structures within a cavernous hemangioma, which may or may not have o...

A 77-year-old female presented with a rare cavernous sinus cavernous hemangioma with extension to the sella turcica, neuroradiologically mimicking nonfunctioning pituitary macroadenoma. The lesion was partially removed via transsphenoidal surgery, and the histological diagnosis was cavernous hemangioma. After stereotactic radiosurgery using a cyber knife, the lesion decreased in size. Stereotac...

Targetoid Hemosiderotic Hemangioma, also known as Hobnail Hemangioma, is a lesion of vascular origin, probably lymphatic. The most common clinical feature is a solitary violaceous papule surrounded by a pale, thin area and a peripheral ecchymotic ring, simulating a target. Histopathologically, there is a biphasic pattern, with dilated vessels in the superficial dermis and pseudoangiosarcomatous...