Acute otitis media in children is very common with an estimated incidence of 85 % within the first year of life. Children usually present with fever, ear fullness, ear discharge and conductive hearing loss. The most common etiologies of acute otitis media in children are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. The diagnosis is based on clinical examination a...

In this study, we propose an automatic diagnostic algorithm for detecting otitis media based on otoscopy images of the tympanic membrane. A total 1336 were assessed by a medical specialist into three groups: acute media, with effusion, and no effusion. To provide proper treatment care limit use unnecessary antibiotics, it is crucial to correctly detect membrane abnormalities, distinguish betwee...

BACKGROUND It is unclear why some children with acute otitis media (AOM) have poor outcomes. Our aim was to describe the clinical course of AOM and the associated bacterial nasopharyngeal colonisation in a high-risk population of Australian Aboriginal children. METHODS We examined Aboriginal children younger than eight years who had a clinical diagnosis of AOM. Pneumatic otoscopy and video-ot...

OBJECTIVE To investigate the efficacy, safety, and microbiology of a thermosensitive otic suspension of ciprofloxacin (OTO-201) in children with bilateral middle ear effusion undergoing tympanostomy tube placement. STUDY DESIGN Two randomized, double-blind, sham-controlled phase 3 trials. Patients were randomized to intratympanic OTO-201 or sham. SETTING Children with bilateral middle ear e...

BACKGROUND Middle ear disease (otitis media) is common and frequently severe in Australian Aboriginal children. There have not been any recent large-scale surveys using clear definitions and a standardised middle ear assessment. The aim of the study was to determine the prevalence of middle ear disease (otitis media) in a high-risk population of young Aboriginal children from remote communities...