Background Tuberculous (TB) meningoencephalitis is an extremely severe condition which requires a quick and correct diagnosis in order to institute a specific etiological treatment in a timely manner. The current “classical” diagnosis of TB meningitis is established through CSF cultures. The result is often inconclusive or is heavily delayed in the case of positive cultures (4-6 weeks). PLEX-ID...

Tuberculosis (TB) is infectious but curable. In South Africa, TB treatment is free of charge at clinic level. However, many patients do not complete their treatment and develop multi-drug resistant TB (MDR-TB) and extensive drug resistant TB (XDR-TB) which is very expensive to treat and can be fatal. The researcher was therefore prompted to investigate how TB patients perceived the disease and ...

A seasonal rise in tuberculosis (TB) notifications has been confirmed in several studies. Here, we examined one hypothesis for its cause: increased transmission of TB during wintertime due to crowding. Seasonality analysis was performed on actual and simulated notifications of clustered TB cases, which are considered to be representative of recent transmission, diagnosed from 1993 to 2004 in th...

Tuberculosis is a systemic disease which involves skeletal and articular system very rarely. Osteoarticular tuberculosis commonly occurs in the vertebral column and more rarely in the sacroiliac joints. In this study, we report a 44-years-old male patient with low-grade fever, malabsorption syndrome, abdominal and pelvic ascites and low-back pain, that underwent 18F-FDG PET/CT for identifying t...

Tuberculosis (TB) is considered to be a disease of poverty, since its incidence is exacerbated by socioeconomic factors, inconsistent or partial treatment practices, and immigration from endemic countries. A prospective country level study, using a comprehensive dataset of TB incidence and prevalence taken from countries within the World Health Organization (WHO) European region, was conducted....

BACKGROUND Reconstruction materials currently used in clinical for osteoarticular tuberculosis (TB) are unsatisfactory due to a variety of reasons. Rifampicin (RFP) is a well-known and highly effective first-line anti-tuberculosis (anti-TB) drug. Poly-DL-lactide (PDLLA) and nano-hydroxyapatite (nHA) are two promising materials that have been used both for orthopedic reconstruction and as carrie...

La tuberculosis (TBC) osteoarticular, causada por una bacteria del género Mycobacterium, representa alrededor de un 10% total TBC extrapulmonares en la edad pediátrica. Su baja prevalencia y su presentación clínica inespecífica conducen a diagnóstico tardío y, con esto, mayor riesgo secuelas. Presentamos serie siete casos pediátricos osteoarticular no vertebral diagnosticados entre el 2006 2019...