This report describes a case of classic severe primary hyperparathyroidism (PH) with clinical presentation that is very infrequent nowadays, which was osteitis fibrosa cystica. As bone scintigraphy demonstrated multiple areas of increasing uptake associated with hypercalcemia, a thorough investigation was conducted to exclude the neoplasms which most frequently are responsible for bone secondar...

Recklinghousen in 1891 were not examples of osteitis fibrosa generalisata and hence of hyperaparathyroidism, but were suffering from "polyostotic fibrous dysplasia." The book concludes with an account of Paget's disease, vith an ingenious, if not very satisfactory, attempt to explain its pathological physiology. It, however, has some useful points in treatment, one or two glasses of milk daily ...

Bone marrow fibrosis occurs in association with a number of pathological states. Despite the extensive fibrosis that sometimes characterizes renal osteodystrophy, little is known about the factors that contribute to marrow accumulation of fibrous tissue. Because circulating cytokines are elevated in uremia, possibly in response to elevated parathyroid hormone levels, we have examined bone biops...

We discuss the weak gravitational field created by isolated matter sources in the Randall-Sundrum brane world. For the case of a single wall of positive tension, the field stays localized near the wall if the source is stationary. We calculate the leading Kaluza-Klein corrections to the linearized gravitational field of a nonrelativistic spherical object, which is different from the Schwarzschi...

Copyright C 2015 by Korean Society of Spine Surgery This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Asian Spine Journal • pISSN 1976-1902 e...

CASE SUMMARY A 4-month-old cat had bilateral swellings of the mandible, maxilla, humerus and femur, and angular deviations in the axial and appendicular skeleton. The biochemical profile indicated hypercalcemia, hyperphosphatemia and increased parathyroid hormone levels. Because of the poor prognosis, the cat was euthanized. At necropsy, malleable and fragile bones, associated with numerous cys...

4 patients with nephrocalcinosis were treated with disodium ethane 1-hydroxy-1, 1-diphosphonate (EHDP) for a period of 13 months. No clinical side-effects were observed and growth proceeded normally. Radiographic changes of osteitis fibrosa cystica developed in 1 child and bone biopsy in 2 children showed defective osteoid mineralisation. It is suggested that EHDP prevented further crystal depo...