BACKGROUND Oral Submucous fibrosis (OSMF) is a common potentially malignant disease, which is characterized by generalized fibrosis of the oral soft tissues. It is due to disproportion in the collagen deposition and degradation. The excess deposition of collagen results in juxta epithelial fibro elastic changes and epithelial atrophy. Neoplastic changes in the epithelium usually precede the cha...

BACKGROUND: Oral Submucous Fibrosis (OSMF) is a chronic, insidious, scarring disease of the mouth often involving palate, oro-pharynx, pharynx, esophagus, tongue and buccal mucosa which leads to ulceration, blanching ultimately limited opening. The aim study describe age, gender district-wise distribution oral submucous fibrosis cases assess malignant transformation rate among patients with who...

Introduction and Objectives: Oral submucous fibrosis (OSMF) is a chronic, progressive, and irreversible disease of the oral mucosa. Though numerous modalities have been tried but all are palliative and have no curative value. Pentoxifylline possessing vasorelaxive and antifibrotic properties believed to potentiate the anti-inflammatory, anti-oxidant and immune modulating properties of garlic. S...

BACKGROUND Oral submucosal fibrosis (OSMF) is one of the most prevalent premalignant conditions in India which is easy to diagnose but difficult to manage. At present it is considered as irreversible and incurable. It has also been referred to as an epidemic in India. AIMS AND OBJECTIVES To correlate the frequency and duration of habits with clinical staging, functional staging and histopatho...

Background: Oral submucous fibrosis (OSMF), now worldwide acknowledged as the disease of “Southeast Asia and Indian subcontinent”, has utmost malignant transformation prevalence amongst oral precancerous disorders. Increased vascularity that is neoangiogenesis been observed in superficial connective tissue region pre-cancerous lesions showing dysplasia. This could be...

Background: Oral cancer is one of the most significant reasons death in India. The quantitative and qualitative assessment AgNORs parameters has been used oncology for both diagnostic prognostic objectives. number distribution AgNOR nucleus (configuration) were helpful detecting predicting prognosis various neoplasias. Aim: To assess biologic aggressiveness leukoplakia, oral submucous fibrosis ...