Odorant receptors (ORs) provide the core determinant of identity for axons of olfactory sensory neurons (OSNs) to coalesce into glomeruli in the olfactory bulb. Here, using gene targeting in mice, we examine how the OR protein determines axonal identity. An OR::GFP fusion protein is present in axons, consistent with a direct function of ORs in axon guidance. When the OR coding region is deleted...

Binary outcome data are common in research and evaluation. They are often analyzed using logistic regression, and results of these analyses are often reported in the form of odds ratios (ORs). However, ORs are not directly interpretable in the metric commonly used in policy-relevant discussions, which concerns probabilities. ORs are unfamiliar to nonresearchers, and their relationship to probab...

Olfactory reference syndrome (ORS) has been defined as a psychiatric condition characterized by persistent preoccupation about body odour accompanied by shame, embarrassment, significant distress, avoidance behaviour and social isolation. ORS has however not been included in the Diagnostic and Statistical Manual of Mental Disorders (4th edition) (DSM-IV) and, given that its primary symptoms may...

Pre- and postabrasion oral rinse samples (ORS) and a toothbrush sample detected human papillomavirus (HPV) DNA in at least one sample among 45 (26%) of 173 HIV-positive men who have sex with men. There was moderate agreement for HPV genotype detection between the preabrasion and postabrasion ORS (κ = 0.49; 95% confidence interval [CI], 0.37 to 0.61). There was good agreement between postabrasio...

Olfactory receptors (ORs) provide the molecular basis for the detection of volatile odorant molecules by olfactory sensory neurons. The OR supergene family encodes G-protein coupled proteins that belong to the seven-transmembrane-domain receptor family. It was initially postulated that ORs are exclusively expressed in the olfactory epithelium. However, recent studies have demonstrated ectopic e...

An anthropological study of knowledge, attitudes and practices relating to child diairhelPand" 'oj specifically to ORS was carried out in Bangladesh. The purpose of the study was to help/flesignja culturally-sensitive social marketing program. Information was gathered on indigenous classifijtgtion of^ p diarrheas, patterns of therapy recourse and diarrhea management, and understanding of petyyd...

We present OpenRichServices (ORS) as an Architecture Definition Language (ADL) for the compositional specification, deployment, and reconfiguration of systems of services. Key distinguishing features of ORS are its treatment of services as first-class citizens of the language, a clean separation between application and infrastructure flows to address cross-cutting concerns at the architectural ...

We evaluated the safety and efficacy of a glycine-based orally administered rehydration solution by comparing it with a standard oral rehydration solution (ORS) without glycine in a randomized double-blind trial in United States infants (age less than 15 months) given treatment for acute gastroenteritis as inpatients or outpatients. The response to therapy (stool volume and duration of illness)...

Rhododendron dauricum L. produces daurichromenic acid, the anti-HIV meroterpenoid consisting of sesquiterpene and orsellinic acid (OSA) moieties. To characterize the enzyme responsible for OSA biosynthesis, a cDNA encoding a novel polyketide synthase (PKS), orcinol synthase (ORS), was cloned from young leaves of R. dauricum. The primary structure of ORS shared relatively low identities to those...

Inventory management of surgical instruments and material handling decisions perioperative services are critical to hospitals’ operating rooms’ (ORs) service levels costs. However, efficiently coordinating these is challenging due their interdependence the uncertainties faced by hospitals. These challenges motivated development this study answer following research questions: (R1) How does inven...