Background & Objectives: The implementation of pest control strategies is essential for reducing food waste and providing fresh safe food product. However, the excessive and uncontrolled usage of pesticides have caused serious environmental and health problems. The aim of this study was to evaluate the level of pesticide residues in food products in Iran via exploring the relevant published wor...

Organophosphorus (OP) and thiocarbamate (TC) agrochemicals are used worldwide as insecticides, herbicides, and fungicides, but their safety assessment in terms of potential off-targets remains incomplete. In this study, a chemoproteomic platform, termed activity-based protein profiling, was used to broadly define serine hydrolase targets in mouse brain of a panel of 29 OP and TC pesticides. Amo...

The sensitivities of acetylcholinesterases (ACHE) from the fungus-feeder Aphelenchus avenae and the plant-parasitic species Helicotylenchus dihystera and Pratylenchus penetrans and the housefly, Musca domestica, were compared using a radiometric assay which utilized H(3) acetylcholine as a substrate. Nematode ACHE were generally less sensitive to inhibition by organophosphorns and carbamate pes...

Although organophosphorus pesticides (OP) share a common mode of action, there is increased awareness that they elicit a diverse range of gene expression responses. As yet however, there is no clear understanding of these responses and how they interact with ambient environmental conditions. In the present study, we investigated genome-wide gene expression profiles in the nematode Caenorhabditi...

Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, clinically available compounds lack broad spectrum, are not effective towards all organophosphorus toxins, have poor pharmacokinetics properties allow them crossing blood-brain barrier, hamper...

We report herein a whole cell-based amperometric biosensor for highly selective, highly sensitive, direct, single-step, rapid, and cost-effective determination of organophosphate pesticides with a p-nitrophenyl substituent. The biosensor was comprised of a p-nitrophenol degrader, Pseudomonas putida JS444, genetically engineered to express organophosphorus hydrolase (OPH) on the cell surface imm...

objective the extensive pollution of natural ecosystems has occurred by organophosphorus pesticides, being used for improvement of crop production in agriculture. biodegradation is interested in application of multifunctional bacteria containing genetical elements which specially degrade organophosphorus compounds. in this paper the detection of two bacteria species, pseudomonas and flavobacter...

Introduction: Chlorpyrifos is an organophosphorus pesticide that is commonly used in agriculture. This toxin is harmful to a wide range of organisms, including living organisms, useful arthropods, fish, birds, humans, animals, and plants. There are many physical, chemical, and biological methods for the removal of organophosphorus pesticides from ecosystems, among which biodegradation is prefer...