In this paper we describe a process called Diegetic Innovation Templating (DiT) whereby science fiction and fantasy stories are used as a systematic source of ideas for design and product innovation. We also introduce a concept called the Diegetic Gap which acts a metric for assessing how compatible a particular piece of fiction is to a given innovation space. We illustrate the Diegetic Innovat...

This study assessed the accuracy of preoperative digital templating for a second-generation cementless stem compared with its first-generation design. A prospective cohort of 100 consecutive patients who had undergone a primary total hip arthroplasty using a new second-generation cementless stem was compared with the prior 100 hips that had received the first-generation stem. The authors believ...

Prion replication occurs via a template-assisted mechanism, which postulates that the folding pattern of a newly recruited polypeptide chain accurately reproduces that of a template. The concept of prion-like template-assisted propagation of an abnormal protein conformation has been expanded to amyloidogenic proteins associated with Alzheimer, Parkinson, Huntington diseases, amyotrophic lateral...

Structures of DNA polymerases bound with DNA reveal that the 5'-trajectory of the template strand is dramatically altered as it exits the polymerase active site. This distortion provides the polymerase access to the nascent base pair to interrogate proper Watson-Crick geometry. Upon binding a correct deoxynucleoside triphosphate, alpha-helix N of DNA polymerase beta is observed to form one face...

Popular web templating languages embed general-purpose programming languages. The Extensible Templating Language was born out of questioning the fundamental assumption that the front-end markup-generating engine of a multi-tier web application requires all the power and expressiveness implied by that design. ETL restricts the set of language features to a useful subset that provide the necessar...

The potential applications of ice-templating porous materials are constantly expanding, especially as scaffolds for tissue engineering. Ice-templating, a process utilizing ice nucleation and growth within an aqueous solution, consists of a cooling stage (before ice nucleation) and a freezing stage (during ice formation). While heat release during cooling can change scaffold isotropy, the freezi...

We report on the use of graphene templating to investigate the room-temperature structure and dynamics of weakly bound adlayers at the interfaces between solids and vapors of small organic molecules. Monolayer graphene sheets are employed to preserve and template molecularly thin adlayers of tetrahydrofuran (THF) and cyclohexane on atomically flat mica substrates, thus permitting a structural c...

The electrodeposition of Ag into organized surfactant templates adsorbed onto (22 × √3) reconstructed Au(111) is investigated by in situ electrochemical scanning tunneling microscopy. Ag(+) concentrations of as low as 2.5 × 10(-6) M allow the visualization of the electrochemical molecular templating effect of a sodium dodecyl sulfate (SDS) adlayer. The SDS hemicylindrical stripes determine the ...

Luminescent metal-organic frameworks (LMOFs) are promising materials for nanophotonic applications due to their tuneable structure and programmability. Yet, the 3D nature of LMOFs creates challenges stability, optical transparency, device integration. Metal-organic nanosheets (MONs) potentially overcome these limitations by combining benefits (MOFs) with an atomically thin morphology large plan...