نتایج جستجو برای: organ dysfunction
تعداد نتایج: 251561 فیلتر نتایج به سال:
OBJECTIVES The purpose of this study was to test whether mitochondrial dysfunction is causative of sepsis sequelae, a mouse model of peritonitis sepsis induced by cecal ligation and perforation. Inhibition of mitochondrial permeability transition was achieved by means of pharmacological drugs and overexpression of the antiapoptotic protein B-cell leukemia (Bcl)-2. BACKGROUND Sepsis is the lea...
Background: Interleukin 6 (IL-6) functions as both a pro-inflammatory cytokine and an anti-inflammatory cytokine. Objective: To evaluate the levels of IL-6 in patients with multiple organ dysfunction syndrome (MODS). Methods: Level of IL-6 was assessed and recorded for 14 days subsequent to the injury in 161 multiple trauma patients. MODS were diagnosed using Marshal Score. Injury Severity Scor...
Acute necrotizing pancreatitis (ANP) is associated with significantlyhighermorbidity and mortality. It still difficult for the surgeon to choose schedule most appropriate treatment.In early phase of disease, surgical activity considered be ineffective high risks. The only chance save patient conduct intensive therapy in care unit, based on current pathogenetic approaches. present review analyze...
Second, why were conventional cooling techniques terminated after 8 hours when the graph (Figure 1 in the report by Broessner and coworkers [1]) indicates that body temperature was effectively lowered to below 39°C (the initial goal in treatment of heat stroke)? We question the cooling technique, because aggressive conventional cooling in the intensive care unit should achieve 39°C within 1 hou...
BACKGROUND The components of nucleosomes, which contain DNA and histones, are released into the circulation from damaged cells and can promote inflammation. We studied whether the on-admission levels of circulating nucleosomes predict the development of severe acute pancreatitis (AP), in particular among the patients who present without clinical signs of organ dysfunction. METHODS This is a p...
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