A small-scale solar organic Rankine cycle (ORC) is a promising renewable energy-driven power generation technology that can be used in the rural areas of developing countries. A prototype was developed and tested for its performance characteristics under a range of solar source temperatures. The solar ORC system power output was calculated based on the thermal and solar collector efficiency. Th...

Initiation of eukaryotic DNA synthesis occurs at origins of replication that are utilized with characteristic times and frequencies during S phase. We have investigated origin usage by evaluating the kinetics of replication factor binding in fission yeast and show that similar to metazoa, ORC binding is periodic during the cell cycle, increasing during mitosis and peaking at M/G1. At an origin,...

Solar-driven organic Rankine cycle (ORC) has been drawing increasing attention due to its high potential in energy conversion efficiency. The two core components of thermal application systems of solar energy are solar collectors and thermal energy storage systems, and many studies have been published. ORC also has attracted much attention in recent years due to its potential in reducing consum...

In late mitosis and G1, origins of DNA replication must be "licensed" for use in the upcoming S phase by being encircled by double hexamers of the minichromosome maintenance proteins MCM2-7. A "licensing checkpoint" delays cells in G1 until sufficient origins have been licensed, but this checkpoint is lost in cancer cells. Inhibition of licensing can therefore kill cancer cells while only delay...

Transactions provide a language construct that programmers can use to specify that operations execute atomically, in isolation from all computation outside the transaction. Transactions permit optimistic concurrency for accesses to shared data, which may improve performance over locking mechanisms. Transactions also allow programmers to specify atomic regions in a composable way, which locks do...

Due to energy shortage and global warming, issues of energy saving have become more important. To increase the energy efficiency and reduce the fuel consumption, waste heat recovery is a significant method for energy saving. The organic Rankine cycle (ORC) has great potential to recover the waste heat from the core jet exhaust of a turbofan engine and use it to produce power. Preliminary study ...

OBJECTIVE Healthcare systems are being challenged to manage increasing numbers of nonhealing wounds. Wound dressings are one of the first lines of defense in wound management, and numerous options exist. The oxidized regenerated cellulose (ORC)/collagen dressing may offer healthcare providers a robust and cost-effective tool for use in a variety of wounds. DESIGN A multidisciplinary panel mee...

PURPOSE The aim of this study was to assess the advantages of robotic surgery, comparing perioperative and oncological outcomes between robot-assisted radical cystectomy (RARC) and open radical cystectomy (ORC). MATERIALS AND METHODS Between August 2008 and May 2014, 112 radical cystectomies (42 RARCs and 70 ORCs) were performed at a single academic institution following Institutional Review ...

Using zeotropic mixtures as working fluids can improve the thermal efficiency of Organic Rankine cycle (ORC) power plants for utilising geothermal energy. However, currently, such ORC systems cannot regulate the composition of zeotropic mixtures when their operating conditions change. A compositionadjustable ORC system could potentially improve the thermal efficiency by closely matching the cyc...

The origin recognition complex (ORC) is a DNA replication initiator protein also known to be involved in diverse cellular functions including gene silencing, sister chromatid cohesion, telomere biology, heterochromatin localization, centromere and centrosome activity, and cytokinesis. We show that, in human cells, multiple ORC subunits associate with hetereochromatin protein 1 (HP1) alpha- and ...