background and objective: basal cell carcinoma (bcc) and squamous cell carcinoma (scc) are two common tumors of the skin. in some cases, distinction between bcc and scc can be difficult. this study aimed to clarify this uncertainty through immunohistochemical analysis. in this respect, epithelial membrane antigen (ema) and ber-ep4 are the two immunohistochemical markers on which we focus in dif...

conclusions the findings of this study are consistent with the hypothesis that local, systemic, or tumor-induced immunosuppression may allow the mcpyv to initiate skin aggressive cancer. it is necessary to maintain regular check over patients taking immunosuppressive medications for mcpyv infection. since there is not any information about detection and molecular biology analysis of mcpyv among...

background: invasive squamous cell carcinoma of the vulva is primarily a disease of postmenopausal women and thus is rarely associated with pregnancy. case: we have reported on a young woman under 40 years old with vulvar carcinoma, which occurred during the pregnancy but optimal treatment was delayed to the postpartum period. this 37-year-old woman was diagnosed with 3x3 cm vulvar lesion, 2 we...

Of all Cancers, Oral cancer is one of the most typical cancers in world. has delayed clinical detection, poor prognosis, without specific biomarkers, and expensive therapeutic methods. This study aims to explain basic aspects oral focuses on squamous cell carcinoma cavity. The duration detection depends amount tobacco usage individual. In this study, we have presented stochastic models for onse...

Verrucous carcinoma (VC) is a rare variant of well differentiated squamous cell carcinoma (SCC) which is usually found in oral cavity mucosa. Cutaneous verrucous carcinoma is a rare entity and in this paper we report a 43 years old man with VC superimposed on chronically inflamed skin of ileostomy site. Previously, he was operated to treat rectal adenocarcinoma and has had ileostomy for six mon...

Objective: To evaluate the frequency and association of p53 gene with increase histopathology categorizing “oral squamous cell carcinoma” patients. Study Design: Comparison Cross-sectional Research. Setting: Isra Dental College Hyderabad. Period: 1 November 2021 to 31 October 2022. Material & Methods: Sixty patients identified oral carcinomas were chosen by consecutive sampling from reporti...

INTRODUCTION Squamous cell carcinoma is the most common malignant tumor of the oral cavity and one of the 10th most common causes of death. It arises from dysplastic oral squamous epithelium. By considering the pathogenesis of squamous cell carcinoma, the smooth and intact surface for this lesion is not usual. CASE PRESENTATION A painful nodular lesion with smooth surface on the left buccal m...

Aim: To determine the Frequency and Pattern of Presentation Oral Squamous Cell Carcinoma its Predisposing Factors in Patients Presented to Nishtar Institute Dentistry. Study design: Cross sectional study. Place Duration Study: was conducted from Aug 2021 Jan 2022 at Methodology: A total 100 patients were included. aged between18-80 years males females included whom presented with oral squamous ...

The mammalian target of rapamycin (mTOR) is engaged in the molecular pathogenesis of oral squamous cell carcinoma, which frequently invades the maxilla or the mandible. However, the effects of a mTOR inhibitor on bone destruction associated with oral squamous cell carcinoma are still unclear. In this study, we investigated the antitumor effect of temsirolimus-mediated mTOR inhibition against ad...

BACKGROUND Esophageal cancer is the 7th most common cancer in Iran. The northern part of the country shows the highest incidence for this malignancy. In this study we present some epidemiological and clinicopathological characteristics of patients with esophageal carcinoma in this region. METHODS In a cross sectional study, 238 Esophageal cancer patients were enrolled in a prospective study o...