background: mucositis is an important adverse effect of cancer treatment. the aim of this study was to investigate the effect of ice cubes on oral mucositis following head and neck radiotherapy. materials and methods: a randomized controlled trial was conducted on 40 head and neck cancer patients who underwent radiotherapy. the patients were randomly divided into two experimental and control gr...

Daily chlorhexidine mouthwash is often recommended for preventing chemotherapy-induced oral mucositis. Povidone-iodine, NaCl 0.9%, water salt soda solution and chamomile mouthwash are also recommended. However, the effectiveness of these mouthwashes is unclear. Therefore, we performed a systematic review to assess the effectiveness of mouthwashes in preventing and ameliorating chemotherapy-indu...

Mucositis is a complex, dose-limiting toxicity of chemotherapy or radiotherapy that leads to painful mouth ulcers, difficulty eating or swallowing, gastrointestinal distress, and reduced quality of life for patients with cancer. Mucositis is most common for those undergoing high-dose chemotherapy and hematopoietic stem cell transplantation and for those being treated for malignancies of the hea...

AIM OF THE STUDY Oral mucositis is a common side effect of the oral mucosa due to anticancer therapy, especially for head and neck cancer. Caphosol is indicated for dryness of the mouth and oropharynx and treatment of mucositis due to irradiation or high-dose chemotherapy. The aim of the study was to evaluate the efficacy of Caphosol in preventing and alleviating mucositis due to radiotherapy i...

OBJECTIVES To assess the efficacy and safety of rebamipide in preventing chemoradiotherapy-induced oral mucositis in patients with oral cancer. MATERIAL AND METHODS Patients with oral cancer treated with chemoradiotherapy (daily radiotherapy plus docetaxel hydrate once a week) were enrolled for this study. They were assigned in a double-blind fashion to receive either rebamipide gargle or pla...

PURPOSE M40403 is a small-molecule superoxide dismutase mimetic that has shown efficacy in animal model disease states in which superoxide anions are thought to play a key role. Radiation treatment and chemotherapy for cancer generate free oxygen radicals that are hypothesized to trigger unwanted side effects in healthy tissue. For some patients undergoing these antineoplastic treatments, one o...

INTRODUCTION Stomatitis is a common and potentially dose-limiting adverse event of the mammalian target of rapamycin (mTOR) inhibitor therapy. To minimize dose reductions or treatment delays that may affect therapeutic outcomes, management includes patient education, pain management strategies, and drug treatment. The aim of this study was to evaluate the effectiveness of a topically-applied ga...

Objective: To assess oral health status and its relationship with stomatological complications, oral mucositis (OM) and odontogenic infections (OI), after dental work in pediatric patients with cancer. Design: Prospective cohort study and analysis of oral health conditions with a 6-month follow-up. Setting: Dental Unit, Stomatology Unit and Oncology Service, Hospital de Clínicas de Porto Alegre...

Radiotherapy in the head and neck region and chemotherapy might give rise to oral mucositis which is a severe and painful inflammation. There is no known definite cure for mucositis. A number of studies have attempted to evaluate the effect of low-power laser on radiotherapy- and chemotherapy-induced mucositis. The present study was undertaken to evaluate the effect of low-power laser on the pr...

Oral health care is a crucial aspect of oncology nursing practice; therefore, this study was conducted to evaluate nurses’ knowledge and practice with oral mucositis (OM) cancer patients undergoing chemotherapy. One hundred nurses were participated from Hiwa Shahid Shaswari Garmian hospitals, in addition demographic, questionnaire designed constructed by the researcher assess nurse’s through Th...