Both irritable bowel syndrome and endometriosis are common conditions, although symptomatic gastrointestinal endometriosis is extremely rare. We report the case of a patient initially thought to have irritable bowel syndrome, in whom the diagnosis of endometriosis only became clear following a laparotomy for small bowel obstruction. This case highlights the need to question the diagnosis in pat...

In the US, medical education does well in developing academic skills, however medicine is much more than academics. Few medical students are prepared for the challenges that await them after the completion of formal training. Relationships with patients, staff, and communities are a particular challenge. Some physicians may choose specialties to ensure that they avoid such challenges. However t...

Ablation for atrial fibrillation (AF) is a genuinely viable and increasingly used option for improving quality of life in patients with symptomatic drug-refractory AF. What is remarkable about the limited success achieved with these procedures is that progress has occurred despite a near complete lack of knowledge about what causes or maintains AF. Focal origins for AF were first demonstrated d...

C omplexes of ruthenium have recently entered clinical trials owing to their potent anticancer activity (1), and those that are photoactive have shown great promise over the past 4 decades in a variety of applications that involve their interaction with DNA, including sensing, signaling, diagnostics, and therapeutics (2, 3). Numerous publications have appeared that focus on the determination of...

To date, measurement-based WCET analysis and static analysis have largely been seen as being at odds with each other. We argue that instead they should be considered complementary, and that the combination of both represents a promising approach that provides benefits over either individual approach. In this paper we discuss in some detail how we aim to improve on our probabilistic measurement-...

After a period marked by one-sided emphasis on psychodynamics and social issues, or what could be called "brainless" psychiatry on account of its relative neglect of cerebral processes, we are witnessing an opposite trend towards extreme biologism or "mindless" psychiatry. The pendulum has swung periodically from one to the other of these reductionistic positions throughout the history of psych...

UNLABELLED There is mounting evidence that early continuous positive airway pressure (CPAP) from birth is feasible and safe even in very preterm infants. However, many infants will develop respiratory distress syndrome (RDS) and require surfactant treatment. Combining a non-invasive ventilation approach with a strategy for surfactant administration is important, but questions remain about the o...

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