purpose: to evaluate the role of transvitreal optic neurotomy (ton) in the management of non-arteritic anterior ischemic optic neurotomy (naion). methods: sixteen eyes of 16 patients with recent onset naion (less than six weeks duration) were included in this single-masked randomized controlled trial. the patients were randomized to ton (8 eyes) versus observation alone (8 eyes). pre- and posto...

Purpose: To discuss aspects of the pathogenesis of glaucomatous optic neuropathy based on morphologic findings of the glaucomatous optic nerve head and examinations of the cerebrospinal fluid pressure. Methods and results: Findings were: normal pressure and high intraocular pressure glaucoma eyes can show a similar appearance of the optic nerve head. These features are not found in any (other) ...

Purpose To report a case of a temporal artery biopsy negative anterior ischemic optic neuropathy associated with a recently completed course of pegylated interferon 2 α with ribavirin for chronic hepatitis C. Observations Despite the early presentation with symptoms and prompt treatment with systemic intravenous steroids the patient experienced deterioration of their optic neuropathy over the...

Thirty seven patients with pendular nystagmus due to multiple sclerosis were reviewed. Most developed nystagmus later in a progressive phase of the disease. All had cerebellar signs on examination and evidence of optic neuropathy. MRI in eight patients showed cerebellar or brainstem lesions in seven; the most consistent finding was a lesion in the dorsal pontine tegmentum. Dissociated nystagmus...

Optic neuropathy, an uncommon manifestation occurs in 5% of patients with Graves' ophthalmopathy. Its outcome is good if early and proper treatment given. We reported a 49 years old male patient of Graves' disease with bilateral optic neuropathy. He underwent bilateral transnasal endoscopic orbital decompression with marked improvement of visual acuity bilaterally. The preoperative visual acuit...

Radiation-induced optic neuropathy is a rare adverse effect of radiotherapy applied for the treatment of pituitary adenomas. We report a patient with a recurrent adrenocorticotrophin secreting pituitary adenoma who received external beam irradiation after failing surgical and medical therapy. Sixteen months after radiotherapy, the patient was presented with declining visual acuity, and radiatio...