نتایج جستجو برای: optic nerve head
تعداد نتایج: 353125 فیلتر نتایج به سال:
INTRODUCTION Drusen of the optic nerve head are relatively benign and asymptomatic. They represent retinal hyaline corpuscles resulting from impaired axoplasmic transport of the retinal ganglion cells of optic nerve in front of the lamina cribrosa. They are usually detected accidentally, during a routine ophthalmologic examination. Most patients with optic disc drusen are not aware of the deter...
PURPOSE As part of a larger project on virtual tissue engineering of the optic pathways, we describe the conditions that guide axons extending from the retina to the optic nerve head and formulate algorithms that meet such conditions. To find the entrance site on the optic nerve head of each axon, we challenge the fibers to comply with current models of axonal pathfinding. METHODS First, we b...
Primary open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease. Intraocular pressure (IOP) and optic nerve head characteristics are used clinically to predict POAG risk. We conducted a genome-wide association meta-analysis of IOP and optic disc parameters and validated our findings in ...
PURPOSE To isolate the rat Myoc/Tigr gene and investigate changes in its expression pattern in normal eyes and in eyes with either pressure-induced optic nerve damage or optic nerve transection. METHODS Expression pattern of the rat Myoc/Tigr gene was investigated by Northern blot hybridization. Optic nerve damage and death of ganglion cells in the retina were induced unilaterally, by injecti...
Laser speckle flowgraphy (LSFG) is an ophthalmologic equipment that qualitatively detects the blood flow of the optic nerve head, which is known to be related with cerebral microcirculation. LSFG can also measure the mean blur rate, which quantitatively calculates the blood flow. We aimed to assess the utility of LSFG in the evaluation of cerebral perfusion during aortic surgery under hypotherm...
The Heidelberg Retina Tomograph (HRT) provides topographic images of the optic nerve head by scanning the eye with a 670nm laser. As a precondition to medical analysis, the optic nerve head has to be outlined manually in clinical practise. Swindale et al. (2000) suggest automated classification of HRT images by a non-linear approximation of the image using the fitted parameters of a non-linear ...
Aim: To evaluate the morphology of the optic nerve head in an unselected population group in south India. Methods: The study included 70 subjects forming a population based sample, selected in a random manner. Mean age was 47.5 (SD 8.7) years, mean refractive error measured −0.07 (1.11) dioptres (range −4.50 to +2.50 dioptres). Optic disc slides were morphometrically analysed. Results: Mean opt...
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