BACKGROUND Basiliximab is a chimeric human/mouse monoclonal antibody directed against the alpha chain of the IL-2 receptor, CD25, which has been reported as successfully reducing rejection in adult renal transplant recipients. Reported clinical experience of basiliximab in paediatric renal transplantation is limited. METHODS Using two intravenous doses on day 0 (pre-operatively) and day 4 wit...

a signed graph (marked graph) is an ordered pair $s=(g,sigma)$$(s=(g,mu))$, where $g=(v,e)$ is a graph called the underlyinggraph of $s$ and $sigma:erightarrow{+,-}$$(mu:vrightarrow{+,-})$ is a function. for a graph $g$, $v(g),e(g)$ and $c(g)$ denote its vertex set, edge set and cut-vertexset, respectively. the lict graph $l_{c}(g)$ of a graph $g=(v,e)$is defined as the graph having vertex set ...

Many animals have genetically determined left-right (LR) asymmetry of their internal organs. The midline structure of vertebrate embryos has important roles in LR asymmetric development both as the signaling center for LR asymmetry and as a barrier to inappropriate LR signaling across the midline. However, in invertebrates, the functions of the midline in LR asymmetric development are unknown. ...

Recessive mutations in the SIAMESE (SIM) gene of Arabidopsis thaliana result in multicellular trichomes harboring individual nuclei with a low ploidy level, a phenotype strikingly different from that of wild-type trichomes, which are single cells with a nuclear DNA content of approximately 16C to 32C. These observations suggested that SIM is required to suppress mitosis as part of the switch to...

OBJECTIVES Systematic information management in hospitals demands for a strategic information management plan (SIM plan). As preparing a SIM plan is a considerable challenge we provide a practical guideline that is directly applicable when a SIM plan is going to be prepared. METHODS The guideline recommends a detailed structure of a SIM plan and gives advice about its content and the preparat...

This study aimed to evaluate the effects of volume adapted re-planning for radiotherapy (RT) after gross total resection (GTR) for glioblastoma. Nineteen patients with glioblastoma who underwent GTR and postoperative RT were analyzed. The volumes of the surgical cavity on computed tomography (CT) obtained one day after GTR (CT0), the first RT simulation CT (sim-CT1), and the second simulation C...

Simvastatin (SIM) is anti-inflammatory. We used low density lipoprotein receptor knockout (LDLR-/-) mice and human aortic smooth muscle cells (HASMCs) as model systems to study the effect of SIM on arterial calcification and to explore the potential mechanisms contributing to this protective effect. High-fat diet (HFD) caused the LRLR -/- to develop dyslipidemia, diabetics, atherosclerosis and ...

The Ligament Advanced Reinforcement System has recently been widely used as the primary graft of choice in anterior cruciate ligament (ACL) reconstruction. But the biological graft-bone healing still remains a problem. Previous studies have shown that simvastatin (SIM) stimulates bone formation. The objective of this study was to investigate whether surface coating with collagen containing low-...

MISQE provides research that impacts practice and can provide valuable insights for senior information technology leaders, chief information officers, IT strategists, and SIM members. The research here takes case studies from industry and develops frameworks which model and share best practices and lessons learned. Most important, the research appearing in MISQE supports a partnership between i...