Due to advances in high-throughput biotechnologies biological information is being collected in databases at an amazing rate, requiring novel computational approaches that process collected data into new knowledge in a timely manner. In this study, we propose a computational framework for discovering modular structure, relationships and regularities in complex data. The framework utilizes a sem...

Starting from the observation that certain communities have incentive mechanisms in place to create large amounts of unstructured content, we propose in this paper an original model which we expect to lead to the large number of annotations required to semantically enrich Web content at a large scale. The novelty of our model lies in the combination of two key ingredients: the effort that onlin...

The "Kitab al-abniya an haqa iq al-adwiya" (Book of the Foundations of Pharmacognosy) also Known as "Rozat ol-ons wa manfa 'ar on-nafs" is the most ancient medical book in Persian (Farsi), which was written by Abu Mansur Movaffaq ibn Ali Heravi during the period of Mansur ibn Noh Samani between the years 350 to 366 lunar hegira. The book deals with 584 mineral, herbal and animal-based drugs. Th...

Motivation Analysis of next-generation sequencing data often results in a list of genomic regions. These may include differentially methylated CpGs/regions, transcription factor binding sites, interacting chromatin regions, or GWAS-associated SNPs, among others. A common analysis step is to annotate such genomic regions to genomic annotations (promoters, exons, enhancers, etc.). Existing tools ...

With more and more cultural heritage data being published online, their usefulness in this open context depends on the quality and diversity of descriptive metadata for collection objects. In many cases, existing metadata is not adequate for a variety of retrieval and research tasks and more specific annotations are necessary. However, eliciting such annotations is a challenge since it often re...

MOTIVATION Linking genes and functional information to genetic variants identified by association studies remains difficult. Resources containing extensive genomic annotations are available but often not fully utilized due to heterogeneous data formats. To enhance their accessibility, we integrated many annotation datasets into a user-friendly webserver. AVAILABILITY AND IMPLEMENTATION http:/...

MOTIVATION Genome-wide association studies (GWAS) generate relationships between hundreds of thousands of single nucleotide polymorphisms (SNPs) and complex phenotypes. The contribution of the traditionally overlooked copy number variations (CNVs) to complex traits is also being actively studied. To facilitate the interpretation of the data and the designing of follow-up experimental validation...

 Personalized Video Krishnan Ramanathan, Yogesh Sankarasubramaniam, Vidhya Govindaraju HP Laboratories HPL-2011-176 Personalization; Online Video; Multimedia retrieval Despite the tremendous growth in online video, the consumption interfaces are still modeled on search-and-browse. We propose a solution to create a much richer online video experience modeled on the television channel metaphor. ...