background and purpose: an important factor involved in infertility is reactive oxygen species (ros). ros can damage sperm dna, and involve lipid per-oxidation. ros elevation is under the influence of leukocyte activation. the objective of this study was to evaluate the level of ros as well as leukocyte, in normozoospermic (no) and ologoasthenoteratozoospermic (oat) ejaculates. materials and me...

The existing evidence suggests that the human reproductive system may be potentially vulnerable to COVID-19 infection. However, little is known about virus–host interaction of in sperm cells. We are first address connection between changes multiple seminal biomarkers and function male patients recovering from COVID-19. In a prospective longitudinal cohort study, ACE2 activity, markers inflammat...

AIM To evaluate for the first time the frequency of Y chromosome microdeletions and the occurrence of the partial deletions of AZFc region in Moroccan men, and to discuss the clinical significance of AZF deletions. METHODS We screened Y chromosome microdeletions and partial deletions of the AZFc region of a consecutive group of infertile men (n = 149) and controls (100 fertile men, 76 normosp...

Introduction Cold-shock precipitating proteins - cryoglobulins damage various vessels and, depending on the localization of damages, may lead to functional disorders of various organs and body systems. Evidently, cryoglobulinemia may have a negative influence on the reproductive system's condition, thus, this process requires detailed study. Material and methods Clinical examples, indicating ...

Reproductive failure is one of the most important issues for the population at age of procreation and approximately 15% of the couples who try to conceive a baby encounter reproductive difficulties. In this study, we used multicolor fluorescent in situ hybridization (FISH) probes for chromosomes 13, 18, 21, X and Y to evaluate the aneuploidy incidence in sperm cells. The study group included 35...

Background: The lipids of the spermatozoa membrane are important for the fluidity and flexibility of spermatozoa. However, spermatozoa’s lipids are the main substrates for peroxidation, which may provoke severe functional disorder of sperm. Objective: The aim of this study was to investigate the fatty acids composition of spermatozoa in men with asthenozoospermia, asthenoteratozoospermia and ol...

BACKGROUND In patients with transient azoospermia, few sperm may be found in the ejaculate. We investigated the outcome of ICSI in patients with transient azoospermia. METHODS Records of patients with transient azoospermia referred during a 42 month period were reviewed. If only immotile sperm were found, the sample was incubated with 30% human serum albumin (HSA) before motility re-assessmen...

Objectives: The present study was conducted to evaluate the relationship between testicular volume measured by using Ultrasonography and seminogram to determine the testicular function in male infertility in Mysore, Karnataka, India. Materials and methods: A total of 274 infertile and 130 normozoospermic males were recruited for this study from Mysore, India. The testicular volumes of all subje...