Mental time travel is the capacity to imagine the autobiographical past and future. Schizotypy is a dimensional measure of psychosis-like traits found to be associated with creativity and imagination. Here, we examine the phenomenological qualities of mental time travel in highly schizotypal individuals. After recollecting past episodes (autobiographical memory) and imagining future events (epi...

During postnatal development, neuronal activity controls the remodeling of initially imprecise neuronal connections through the regulation of gene expression. MeCP2 binds to methylated DNA and modulates gene expression during neuronal development and MECP2 mutation causes the autistic disorder Rett syndrome. To investigate a role for MeCP2 in neuronal circuit refinement and to identify activity...

organization of various cells lining the olfactory mucosa of puntius ticto (hamilton, 1822) were described by light as well as scanning electron microscopy. the paired olfactory chambers located antero-dorsal to the eyes and communicated outside through anterior and posterior nasal openings. the oval shaped olfactory rosette lied at the bottom of chamber and composed of 18-20 lamellae arranged ...

Background: About 50% of stroke patients suffer from the disorder of consciousness with such adverse effects as sensory deprivation. The provision of a care program consisting of simple and safe stimulations can prevent sensory deprivation and improve the patient’s sensory function. Aim: This study aimed to determine the effect of structured sensory stimulation program on the sensory function o...

* Present address: Biological Research Lab., Tanabe Seiyaku Co ., Ltd., Osaka, Japan. Abstract-In order to clarify the neural mechanisms underlying the hyperemotion ality induced by bilateral olfactory bulb ablations in rats, changes in emotional be havior were measured after various parts of the secondary olfactory structures had been lesioned and olfactory bulb ablations had been carried out....

BACKGROUND Research into the pathophysiology of bipolar disorder (BD) is limited by the inability to examine brain cellular processes in subjects with the illness. METHODS Endoscopic biopsy was performed in subjects with bipolar I disorder to establish olfactory neural progenitor (ONP) cell lines. Olfactory function was assessed prebiopsy and postbiopsy using the University of Pennsylvania Sm...

BACKGROUND Patients with a smell disorder and less often, healthy people, exhibit an olfactory difference between the two sides of the nose. Higher olfactory thresholds are correlated with the obstructed side of a nasal septal deviation (NSD). With this prospective study we sought to investigate if a NSD compromises the olfactory identification. MATERIALS AND METHODS Thirty patients with nasa...

Post-Covid Olfactory Dysfunction (PCOD) is characterized by olfactory abnormalities, hyposmia, and anosmia, which are among the most often enduring symptoms in individuals who have recovered from SARS-CoV-2 infection. This disorder has been reported to persist subsets of patients well after 12 months following infection, significantly affecting their quality life. Despite high prevalence PCOD s...

Olfaction plays an important role in emotions in our daily life. Pleasant odors are known to evoke positive emotions, inducing relaxation and calmness. The beneficial effects of vanillin on depressive model rats were investigated using a combination of behavioral assessments and neurotransmitter measurements. Before and after chronic stress condition (or olfactory bulbectomy), and at the end of...