Introduction Mucopolysaccharidoses (MPS) are a group of metabolic disorders caused by the absence or inadequate functioning of enzymes needed to break down glycosaminoglycans (GAG), which are essential structural elements of many tissues in the human body (bone, cartilage, cornea, skin, connective tissue). One of the main features of several of the mucopolysaccharidoses is bone damage and remod...

AIMS To assess whether the use of beta-blockers influences mortality and the incidence of major cardiovascular events in patients with diabetes and coronary heart disease (CHD). MATERIALS AND METHODS Using data from the Bypass Angioplasty Revascularization Investigation 2 Diabetes trial, we performed Cox proportional hazards analysis to assess the effects of β-blockers on all-cause mortality ...

Determining the upper treeline is certainly one of the most interesting research challenges in comparative high mountain research. Careful compilations (Hermes 1955; von Wissmann 1961; Schickhoff 2005) have documented that the highest treelines in the northern hemisphere are found on the eastern declivity of the Tibetan Highlands. However, regional and global synopses of upper treeline altitude...

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7. Pillai SK, Sakoulas G, Wennersten C, Eliopoulos GM, Moellering RC Jr, Ferraro MJ, et al. Linezolid resistance in Staphylococcus aureus: characterization and stability of resistant phenotype. J Infect Dis. 2002;186:1603–7. DOI: 10.1086/345368 8. Mendes RE, Deshpande LM, Castanheira M, DiPersio J, Saubolle MA, Jones RN. First report of cfr-mediated resistance to linezolid in human staphylococc...