OBJECTIVES The present study evaluated the beneficial effects of omega 3 PUFA present in fish oil on neurosensorial impairments, namely learning, memory and anxiety in Streptozotocin (STZ) induced diabetic rats. The brain homogenate was analysed for oxidative status following Omega 3 PUFA treatment. METHODS Male, Wistar rats of 2-3 months old were divided into non diabetic controls, diabetic ...

The Amazon rainforest is the largest reserve of natural products in the world. Its rich biodiversity of medicinal plants has been utilized by local populations for hundreds of years for the prevention and treatment of various diseases and ailments. Oil extracts from plant species such as Copaifera officinalis and Pentaclethra macroloba are used in compounded formulations for their antiinflammat...

The new coronavirus associated with severe acute respiratory syndrome (SARS-CoV-2), surprisingly, does not affect only the lungs. response to SARS-CoV-2 appears include a “cytokine storm,” which indicates state of hyperinflammation and subsequent dysfunction multiple organs tissues in most cases. This could be reason why populations at highest risk for death from infection–induced disease (coro...

Attempts were made to prevent methylcholanthrene tumorigenesis in mice by immunization with the insoluble lipoprotein of methylcholanthrene-induced sarcomas of the same strain of mice. Swiss/Mk mice were intensively immunized with the insoluble lipoprotein fraction extracted by the Thomas method or with the supernatant fraction of isogenic methylcholanthrene-induced tumor cells, or normal cells...

background outer membrane protein d (pd) is a highly conserved and stable protein in the outer membrane of both encapsulated (typeable) and non-capsulated (non-typeable) strains of haemophilus influenzae. as an immunogen, pd is a potential candidate vaccine against non-typeable h. influenzae (nthi) strains. objectives the aim of this study was to determine the cytokine pattern and the opsonic a...

Background: It has been reported that vitamin D has broad anti-inflammatory and immunomodulatory effects. Objective: To evaluate the effects of vitamin D on the expression of IL-27 and IL-33 in a model of experimental autoimmune encephalomyelitis (EAE). Methods: EAE was induced in C57BL/6 mice by immunization with myelin oligodendroglial glycoprotein mixed with complete Freund's adjuvant. The m...

The grease gun injury is an uncommon injury to the orbit. However, high-pressure injection of grease, oil, or paint is frequently reported in injuries of the hand and usually affects the fingers or palm, which require complicated surgical and medical care. Two cases of grease gun injury to the orbit are reported: one, a catastrophic injury, and the other resulting in satisfactory recovery after...