18 Odorants inhibit as well as excite olfactory receptor neurons (ORNs) in many 19 species of animals. Cyclic nucleotide-dependent activation of canonical mammalian 20 ORNs is well established but it is still unclear how odorants inhibit these cells. Here we 21 further implicate phosphoinositide-3-kinase (PI3K), an indispensable element of PI 22 signaling in many cellular processes, in olfactor...

People assess the quality of the air indoors primarily on the basis of its odors and on their perception of associated health risk. The major current contributors to indoor odorants are human occupant odors (body odor), environmental tobacco smoke, volatile building materials, bio-odorants (particularly mold and animal-derived materials), air fresheners, deodorants, and perfumes. These are most...

The aim of this paper is to analyse the relationship between self-report hedonic evaluations and the physiological expression of emotion in response to odorants. We try to solve the following questions: (1) Is it possible to find any experimental evidence that the sense of smell is linked with emotion? (2) What kind of odorants can be distinguished by autonomic analysis? (3) Is there a link bet...

The present study compared the relative effectiveness of simple, commercially available food and non-food olfactory tasks on chocolate craving reduction. Chocolate cravings were induced by a series of coloured photographs and 67 undergraduate women were asked to smell one of three odours (green apple, jasmine, or water). The non-food odorant (jasmine) significantly reduced chocolate cravings re...

We investigated the relationship between odor codability and odor memory representation in three cultural groups: French, American, and Vietnamese. In a first experiment, we asked participants from the three cultures to identify twice a set of 40 common odorants. From this task, we computed the codability of each of the 40 odorants. In a second experiment, we asked another group of participants...

Odorants activate receptors in the peripheral olfactory neurons, which sends information to higher brain centers where behavioral valence is determined. Movement and airflow continuously change what odor plumes an animal encounters and little is known about the effect one plume has on the detection of another. Using the simple Drosophila melanogaster larval model to study this relationship we i...

Chronically high occupational exposure to airborne metals like iron can impair olfactory function, but little is known about how low iron status modifies olfactory behavior. To investigate the influence of body iron status, weanling rats were fed a diet with low iron content (4 - 7 ppm) to induce iron deficiency anemia and olfactory behavior was compared to control rats fed an isocaloric diet s...