The aim of this study was to investigate whether there is any association between inflammation and the expression of markers of cell cycle entry (Ki-67 and MCM-2) in dental follicle (DF) of asymptomatic impacted teeth and odontogenic cysts. The study consisted of 70 DFs and 20 odontogenic cysts (radicular cyst (RC), dentigerous cyst (DC) and keratocytic odontogenic tumor (KCOT) located at poste...

Odontogenesis occurs because of a multi-stage complicated interaction between the oral epithelium and the mesenchymal tissue under the epithelium. Abnormal tissue interactions during this process can lead to ectopic tooth development (1). Ectopic tooth outside the oral cavity is rarely reported in the literature (1, 2) Ectopic teeth can be asymptomatic or can form odontogenic cysts, cause degra...

Ameloblastic fibro-odontoma (AFO) predominantly occurs in the jaw bones of children and young adults. Extraosseous AFO is extremely rare. We describe a peripheral ameloblastic fibro-odontoma in the maxillary gingiva of a 3-year-old girl. The clinical appearance resembled fiery red reactive gingival lesions. The histopathological examination of the excised lesion showed small islands and cords o...

Cyst is defined as a pathological cavity which may or not be lined by an epithelium and usually filled with solid, semisolid gaseous material. Dentigerous cyst of odontogenic origin associated impacted tooth. in maxillary antrum often misdiagnosed peripheral health care centers due to initial complaints mimicking sinusitis patients reporting general physicians/otolaryngologist for treatment. Th...

INTRODUCTION The lateral periodontal cyst, as the name implies, occurs on a lateral periodontal location and is of developmental origin, arising from cystic degeneration of clear cells of the dental lamina. A botryoid odontogenic cyst is considered to be a rare multilocular variant of a lateral periodontal cyst. CASE PRESENTATION We report the clinical and histopathologic features of a rare c...

Peripheral ameloblastoma (PA) is a rare extraosseous odontogenic tumor with histological characteristics similar to those of the common intraosseous ameloblastoma. Two questions regarding PA remain: its histogenic origin and how to differentiate between PA and intraoral basal cell carcinoma. We describe a patient with PA. The result of immunohistochemistry showed cytokeratin (CK) 7-, CK14+, CK1...

Unicystic ameloblastoma is a rare, benign, locally invasive odontogenic neoplasm of young age that shows clinical, radiographical or gross features of an odontogenic cyst, but it histologically shows typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor growth. A case of asymptomatic unicystic ameloblastoma in an 11- year-old-female, who...

  Objective: The Ortho keratinized Odontogenic Cyst (OOC) is a rare lesion originates from dental lamina and clinically, it may be mistaken for many other odontogenic cysts and Tumors. Microscopically, It should be distinguished from KCOT because of differences in biologic behavior and histologic features.   Case: An interesting case of OOC arising in the edentulous mandibular right first premo...

Central odontogenic fi broma (COF) is a rare benign odontogenic tumor characterized by variable amounts of inactive-looking odontogenic epithelium embedded in a mature fi brous stroma corresponding to 0-5.5% of all odontogenic tumors. COF may be seen at any age, but it is diagnosed most frequently in patients between the second and fourth decades of life. The lesion is asymptomatic except the s...

Calcifying odontogenic cyst (COC) is a term used broadly to define lesions which were either cystic/solid in nature. However, a new term defining dentinogenic ghost cell tumor (DGCT), as its neoplastic counterpart, histopathologically showed the presence of dentinoid-like areas, ghost cells and ameloblastomatous-like odontogenic epithelium. This possesses a great challenge to an oral pathologis...